A Lipid-Soluble Red Ginseng Extract Inhibits the Growth of Human Lung Tumor Xenografts in Nude Mice
DC Field | Value | Language |
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dc.contributor.author | Lee, Sung Dong | - |
dc.contributor.author | Park, Song-Kyu | - |
dc.contributor.author | Lee, Eun Sil | - |
dc.contributor.author | Kim, Hwan Mook | - |
dc.contributor.author | Lee, Chang Woo | - |
dc.contributor.author | Lee, Kiho | - |
dc.contributor.author | Lee, Ki Hoon | - |
dc.contributor.author | Kang, Moo Rim | - |
dc.contributor.author | Lee, Kwang Seung | - |
dc.contributor.author | Lee, Junsoo | - |
dc.contributor.author | Hwang, Woo Ik | - |
dc.contributor.author | Kim, Dong Chung | - |
dc.date.accessioned | 2021-09-08T05:34:41Z | - |
dc.date.available | 2021-09-08T05:34:41Z | - |
dc.date.created | 2021-06-11 | - |
dc.date.issued | 2010-02 | - |
dc.identifier.issn | 1096-620X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/117101 | - |
dc.description.abstract | Lipid-soluble ginseng extract was prepared by n-hexane extraction of red ginseng. BALB/c-nu mice were inoculated with human lung cancer (NCI-H460) cells to establish a human tumor xenograft model in nude mice, and the lipid-soluble ginseng extract was orally administered. The tumor inhibitory rates of the lipid-soluble ginseng extract at doses of 0.1, 0.3, and 1.0 g/kg/day were 18.9% (P<.05), 60.0% (P<.001), and 67.5% (P<.001), respectively. The oral administration of the lipid-soluble extract of red ginseng showed a potent anticancer effect in nude mice bearing human lung cancer cells in a dose-dependent manner without any apparent toxicity. This lipid-soluble ginseng extract is a potential nontoxic anticancer supplement for the prevention and intervention of lung tumor growth through an oral administration route. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | MARY ANN LIEBERT, INC | - |
dc.subject | CELL-PROLIFERATION | - |
dc.subject | CANCER CELLS | - |
dc.subject | INDUCTION | - |
dc.subject | APOPTOSIS | - |
dc.subject | SURVIVAL | - |
dc.subject | RH-2 | - |
dc.subject | RATS | - |
dc.title | A Lipid-Soluble Red Ginseng Extract Inhibits the Growth of Human Lung Tumor Xenografts in Nude Mice | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Sung Dong | - |
dc.contributor.affiliatedAuthor | Park, Song-Kyu | - |
dc.contributor.affiliatedAuthor | Kim, Hwan Mook | - |
dc.contributor.affiliatedAuthor | Lee, Kiho | - |
dc.contributor.affiliatedAuthor | Hwang, Woo Ik | - |
dc.identifier.doi | 10.1089/jmf.2009.1142 | - |
dc.identifier.scopusid | 2-s2.0-76649096690 | - |
dc.identifier.wosid | 000274329600001 | - |
dc.identifier.bibliographicCitation | JOURNAL OF MEDICINAL FOOD, v.13, no.1, pp.1 - 5 | - |
dc.relation.isPartOf | JOURNAL OF MEDICINAL FOOD | - |
dc.citation.title | JOURNAL OF MEDICINAL FOOD | - |
dc.citation.volume | 13 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 5 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001421186 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalResearchArea | Nutrition & Dietetics | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Nutrition & Dietetics | - |
dc.subject.keywordPlus | CELL-PROLIFERATION | - |
dc.subject.keywordPlus | CANCER CELLS | - |
dc.subject.keywordPlus | INDUCTION | - |
dc.subject.keywordPlus | APOPTOSIS | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | RH-2 | - |
dc.subject.keywordPlus | RATS | - |
dc.subject.keywordAuthor | anticancer effect | - |
dc.subject.keywordAuthor | human tumor xenograft | - |
dc.subject.keywordAuthor | lipid-soluble ginseng extract | - |
dc.subject.keywordAuthor | oral administration | - |
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