3년간 치료를 지속한 정신과 외래 노인 환자에서의 다제요법에 대한 연구A Study on Polypharmacy in the Elderly Psychiatric Outpatients with Persistent Treatments for 3 years
- Other Titles
- A Study on Polypharmacy in the Elderly Psychiatric Outpatients with Persistent Treatments for 3 years
- Authors
- 유해선; 정인과
- Issue Date
- 2010
- Publisher
- 대한노인정신의학회
- Keywords
- The elderly·Polypharmacy·Psychiatric drugs; 노인·다제요법·정신과적 약물
- Citation
- 노인정신의학, v.14, no.1, pp.50 - 57
- Indexed
- KCI
OTHER
- Journal Title
- 노인정신의학
- Volume
- 14
- Number
- 1
- Start Page
- 50
- End Page
- 57
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/117353
- ISSN
- 1226-6329
- Abstract
- Objectives:The objective of this study was to investigate the prescription trends for the elderly psychiatric outpatients at a university hospital.
Methods:We performed a retrospective study based on medical records. Data on 146 elderly patients (65 years and older) diagnosed with psychiatric disorders according to ICD-10 from January 2005 to March 2008 were collected. Analyses were performed regarding demographic characteristics, prevalence of polypharmacy, and the doses and types of drugs prescribed.
Results:In 146 subjects, the mean age was 76.14±5.21. More than five types of drugs were prescribed to 49.5% of the patients in 2008. The percentage of stable users (those without changes in the category of polypharmacy for 3 years) was 69.8%. Each patient received an average of 4.20±1.50 kinds of drugs in 2005 and 4.02±1.77 in 2008. The average dose of drugs was 6.1±3.50 in 2005 and 6.49±4.09 in 2008, and the difference was not statistically significant. The average number of types of psychiatric drugs prescribed to the patients decreased from 2.37±0.86 in 2005 to 2.17±0.87 in 2008 (p<0.05).
Conclusion:Although practice of polypharmacy showed a slow increase over the 3 years from 2005 to 2008, almost half of the elderly patients we studied received multiple drugs. Since polypharmacy can increase drug-drug interactions and adverse effects in the elderly, appropriate drug monitoring and careful prescription are necessary.
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