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Reliability and data integration of duplicated test results using two bioelectrical impedence analysis machines in the Korean genome and epidemiology study

Authors
Park, B.Yang, J.J.Yang, J.H.Kim, J.Cho, L.Y.Kang, D.Shin, C.Hong, Y.S.Choi, B.Y.Kim, S.S.Park, M.S.Park, S.K.
Issue Date
2010
Keywords
Electric impedance; Regression; Statistical model
Citation
Journal of Preventive Medicine and Public Health, v.43, no.6, pp.479 - 485
Indexed
SCOPUS
KCI
Journal Title
Journal of Preventive Medicine and Public Health
Volume
43
Number
6
Start Page
479
End Page
485
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/118242
DOI
10.3961/jpmph.2010.43.6.479
ISSN
1975-8375
Abstract
Objectives: The Korean Genome and Epidemiology Study (KoGES), a multicenter-based multi-cohort study, has collected information on body composition using two different bioelectrical impedence analysis (BIA) machines. The aim of the study was to evaluate the possibility of whether the test values measured from different BIA machines can be integrated through statistical adjustment algorithm under excellent inter-rater reliability. Methods: We selected two centers to measure inter-rater reliability of the two BIA machines. We set up the two machines side by side and measured subjects' body compositions between October and December 2007. Duplicated test values of 848 subjects were collected. Pearson and intra-class correlation coefficients for inter-rater reliability were estimated using results from the two machines. To detect the feasibility for data integration, we constructed statistical compensation models using linear regression models with residual analysis and R-square values. Results: All correlation coefficients indicated excellent reliability except mineral mass. However, models using only duplicated body composition values for data integration were not feasible due to relatively low R2 values of 0.8 for mineral mass and target weight. To integrate body composition data, models adjusted for four empirical variables that were age, sex, weight and height were most ideal (all R2>0.9). Conclusions: The test values measured with the two BIA machines in the KoGES have excellent reliability for the nine body composition values. Based on reliability, values can be integrated through algorithmic statistical adjustment using regression equations that includes age, sex, weight, and height.
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