Manufacturing of iron binding peptide using sericin hydrolysate and its bioavailability in iron deficient rat
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cho, H.J. | - |
dc.contributor.author | Lee, H.-S. | - |
dc.contributor.author | Jung, E.Y. | - |
dc.contributor.author | Park, S.Y. | - |
dc.contributor.author | Lim, W.-T. | - |
dc.contributor.author | Lee, J.-Y. | - |
dc.contributor.author | Yeon, S.-H. | - |
dc.contributor.author | Lee, J.-C. | - |
dc.contributor.author | Suh, H.J. | - |
dc.date.accessioned | 2021-09-08T09:19:31Z | - |
dc.date.available | 2021-09-08T09:19:31Z | - |
dc.date.created | 2021-06-17 | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1226-3311 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/118316 | - |
dc.description.abstract | Silk sericin protein was hydrolyzed by seven proteolytic enzymes to examine the effectiveness of the hydrolysates to bind iron. The amino acid nitrogen contents of hydrolysates by Flavourzyme were higher than the others enzymes, and its iron binding capacity showed dose-dependent increase. The bioavailability of iron binding peptide from sericin hydolysates was investigated in iron-deficient rats. Three-week-old male rats were fed iron-deficient diet for three weeks. Rats were divided into four groups (DD: no treated group on iron deficient diet, DD+HI: heme-iron treated group, DD+OI: sericin-Fe, and DD+II: inorganic iron (FeSO4) treated group, and then iron supplemented by injection for one week. After oral administration for one week, the iron contents of serum and liver were significantly higher in DD+OI (4.2 μg/mL and 80.1 μg/mL) and DD+HI (3.2 μg/mL and 70.6 μg/mL) than DD (2.0 μg/mL and 47.9 μg/mL). Hemoglobin content of treated groups was significantly higher than DD, but the significant difference among groups was not shown. Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels did not show any significant difference among all groups. Binding iron to peptide from sericin hydolysates seems to improve its bioavailability and to hasten the cure of iron deficiency in experimental rat. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.subject | Rattus | - |
dc.title | Manufacturing of iron binding peptide using sericin hydrolysate and its bioavailability in iron deficient rat | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, H.-S. | - |
dc.contributor.affiliatedAuthor | Jung, E.Y. | - |
dc.contributor.affiliatedAuthor | Suh, H.J. | - |
dc.identifier.doi | 10.3746/jkfn.2010.39.10.1446 | - |
dc.identifier.scopusid | 2-s2.0-80052321697 | - |
dc.identifier.bibliographicCitation | Journal of the Korean Society of Food Science and Nutrition, v.39, no.10, pp.1446 - 1451 | - |
dc.relation.isPartOf | Journal of the Korean Society of Food Science and Nutrition | - |
dc.citation.title | Journal of the Korean Society of Food Science and Nutrition | - |
dc.citation.volume | 39 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1446 | - |
dc.citation.endPage | 1451 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001491826 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordPlus | Rattus | - |
dc.subject.keywordAuthor | Bioavailability | - |
dc.subject.keywordAuthor | Iron | - |
dc.subject.keywordAuthor | Iron binding peptide | - |
dc.subject.keywordAuthor | Sericin hydrolysate | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.