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Inhibitors of nitric oxide production from Artemisia princeps
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Li, D. | - |
| dc.contributor.author | Han, X.H. | - |
| dc.contributor.author | Hong, S.S. | - |
| dc.contributor.author | Lee, C. | - |
| dc.contributor.author | Lee, M.S. | - |
| dc.contributor.author | Lee, D. | - |
| dc.contributor.author | Lee, M.K. | - |
| dc.contributor.author | Hwang, B.Y. | - |
| dc.date.accessioned | 2021-09-08T09:19:55Z | - |
| dc.date.available | 2021-09-08T09:19:55Z | - |
| dc.date.created | 2021-06-17 | - |
| dc.date.issued | 2010 | - |
| dc.identifier.issn | 1226-3907 | - |
| dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/118318 | - |
| dc.description.abstract | The chromatographic separation of a methanol extract of Artemisia princes led to the isolation of two sesquiterpene lactones, artecanin (1) and canin (2), together with a flavonoid, eupatilin (3). Their structures were determined by 1D, 2D-NMR and MS data analysis. All of the isolates were evaluated for their potential to inhibit the LPS-induced production of nitric oxide in murine macrophage RAW 264.7 cells. Compounds 1-3 inhibited nitric oxide production with IC50 values of 19.5, 20.4 and 25.1 μM, respectively. | - |
| dc.language | English | - |
| dc.language.iso | en | - |
| dc.subject | artecanin | - |
| dc.subject | canin | - |
| dc.subject | eupatilin | - |
| dc.subject | flavanoid | - |
| dc.subject | lipopolysaccharide | - |
| dc.subject | methanol | - |
| dc.subject | nitric oxide synthase inhibitor | - |
| dc.subject | sesquiterpene lactone | - |
| dc.subject | unclassified drug | - |
| dc.subject | animal cell | - |
| dc.subject | artemisia princeps | - |
| dc.subject | article | - |
| dc.subject | carbon nuclear magnetic resonance | - |
| dc.subject | drug isolation | - |
| dc.subject | drug mechanism | - |
| dc.subject | drug structure | - |
| dc.subject | drug synthesis | - |
| dc.subject | IC 50 | - |
| dc.subject | macrophage | - |
| dc.subject | mass spectrometry | - |
| dc.subject | medicinal plant | - |
| dc.subject | mouse | - |
| dc.subject | nonhuman | - |
| dc.subject | nuclear Overhauser effect | - |
| dc.subject | proton nuclear magnetic resonance | - |
| dc.subject | thin layer chromatography | - |
| dc.title | Inhibitors of nitric oxide production from Artemisia princeps | - |
| dc.type | Article | - |
| dc.contributor.affiliatedAuthor | Lee, D. | - |
| dc.identifier.scopusid | 2-s2.0-78650526057 | - |
| dc.identifier.bibliographicCitation | Natural Product Sciences, v.16, no.3, pp.143 - 147 | - |
| dc.relation.isPartOf | Natural Product Sciences | - |
| dc.citation.title | Natural Product Sciences | - |
| dc.citation.volume | 16 | - |
| dc.citation.number | 3 | - |
| dc.citation.startPage | 143 | - |
| dc.citation.endPage | 147 | - |
| dc.type.rims | ART | - |
| dc.type.docType | Article | - |
| dc.identifier.kciid | ART001482364 | - |
| dc.description.journalClass | 1 | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.description.journalRegisteredClass | kci | - |
| dc.subject.keywordPlus | mass spectrometry | - |
| dc.subject.keywordPlus | medicinal plant | - |
| dc.subject.keywordPlus | mouse | - |
| dc.subject.keywordPlus | nonhuman | - |
| dc.subject.keywordPlus | nuclear Overhauser effect | - |
| dc.subject.keywordPlus | proton nuclear magnetic resonance | - |
| dc.subject.keywordPlus | thin layer chromatography | - |
| dc.subject.keywordPlus | artecanin | - |
| dc.subject.keywordPlus | canin | - |
| dc.subject.keywordPlus | eupatilin | - |
| dc.subject.keywordPlus | flavanoid | - |
| dc.subject.keywordPlus | lipopolysaccharide | - |
| dc.subject.keywordPlus | methanol | - |
| dc.subject.keywordPlus | nitric oxide synthase inhibitor | - |
| dc.subject.keywordPlus | sesquiterpene lactone | - |
| dc.subject.keywordPlus | unclassified drug | - |
| dc.subject.keywordPlus | animal cell | - |
| dc.subject.keywordPlus | artemisia princeps | - |
| dc.subject.keywordPlus | article | - |
| dc.subject.keywordPlus | carbon nuclear magnetic resonance | - |
| dc.subject.keywordPlus | drug isolation | - |
| dc.subject.keywordPlus | drug mechanism | - |
| dc.subject.keywordPlus | drug structure | - |
| dc.subject.keywordPlus | drug synthesis | - |
| dc.subject.keywordPlus | IC 50 | - |
| dc.subject.keywordPlus | macrophage | - |
| dc.subject.keywordAuthor | Artemisia princeps | - |
| dc.subject.keywordAuthor | Compositae | - |
| dc.subject.keywordAuthor | Nitric oxide production inhibitor | - |
| dc.subject.keywordAuthor | Sesquiterpene lactone | - |
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