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In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles

Authors
Koo, HeebeomLee, HyejungLee, SojinMin, Kyung HyunKim, Min SangLee, Doo SungChoi, YongseokKwon, Ick ChanKim, KwangmeyungJeong, Seo Young
Issue Date
2010
Publisher
ROYAL SOC CHEMISTRY
Citation
CHEMICAL COMMUNICATIONS, v.46, no.31, pp.5668 - 5670
Indexed
SCIE
SCOPUS
Journal Title
CHEMICAL COMMUNICATIONS
Volume
46
Number
31
Start Page
5668
End Page
5670
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/118659
DOI
10.1039/c0cc01413c
ISSN
1359-7345
Abstract
We report protoporphyrin IX (PpIX) encapsulated pH-responsive micelles for cancer treatment. This system showed pH-responsive micellization/demicellization transition at tumoral acidic pH and enabled in vivo tumor diagnosis and therapy simultaneously.
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