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Nonblinking and Nonbleaching Upconverting Nanoparticles as an Optical Imaging Nanoprobe and T1 Magnetic Resonance Imaging Contrast Agent
- Authors
- Park, Yong Il; Kim, Jeong Hyun; Lee, Kang Taek; Jeon, Ki-Seok; Bin Na, Hyon; Yu, Jung Ho; Kim, Hyung Min; Lee, Nohyun; Choi, Seung Hong; Baik, Sung-Il; Kim, Hyoungsu; Park, Seung Pyo; Park, Beom-Jin; Kim, Young Woon; Lee, Sung Ho; Yoon, Soo-Young; Song, In Chan; Moon, Woo Kyung; Suh, Yung Doug; Hyeon, Taeghwan
- Issue Date
- 26-11월-2009
- Publisher
- WILEY-V C H VERLAG GMBH
- Citation
- ADVANCED MATERIALS, v.21, no.44, pp.4467 - +
- Indexed
- SCIE
SCOPUS
- Journal Title
- ADVANCED MATERIALS
- Volume
- 21
- Number
- 44
- Start Page
- 4467
- End Page
- +
- ISSN
- 0935-9648
- Abstract
- Core/shell upconverting nanoparticles (UCNPs) of NaGdF4:Er3+, Yb3+/NaGdF4 (see figure) are shown to serve as a multimodal imaging probe that works for both background-free optical imaging and magnetic resonance imaging (MRI). The nonblinking and nonbleaching properties of UCNPs can contribute to minimization of possible artifacts in long-term imaging experiments. Owing to Gd3+ ions in the host matrix, contrast is enhanced in T-1-weighted MRI.
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