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Nonblinking and Nonbleaching Upconverting Nanoparticles as an Optical Imaging Nanoprobe and T1 Magnetic Resonance Imaging Contrast Agent

Authors
Park, Yong IlKim, Jeong HyunLee, Kang TaekJeon, Ki-SeokBin Na, HyonYu, Jung HoKim, Hyung MinLee, NohyunChoi, Seung HongBaik, Sung-IlKim, HyoungsuPark, Seung PyoPark, Beom-JinKim, Young WoonLee, Sung HoYoon, Soo-YoungSong, In ChanMoon, Woo KyungSuh, Yung DougHyeon, Taeghwan
Issue Date
26-11월-2009
Publisher
WILEY-V C H VERLAG GMBH
Citation
ADVANCED MATERIALS, v.21, no.44, pp.4467 - +
Indexed
SCIE
SCOPUS
Journal Title
ADVANCED MATERIALS
Volume
21
Number
44
Start Page
4467
End Page
+
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/118898
DOI
10.1002/adma.200901356
ISSN
0935-9648
Abstract
Core/shell upconverting nanoparticles (UCNPs) of NaGdF4:Er3+, Yb3+/NaGdF4 (see figure) are shown to serve as a multimodal imaging probe that works for both background-free optical imaging and magnetic resonance imaging (MRI). The nonblinking and nonbleaching properties of UCNPs can contribute to minimization of possible artifacts in long-term imaging experiments. Owing to Gd3+ ions in the host matrix, contrast is enhanced in T-1-weighted MRI.
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