Identification of Antiadipogenic Constituents of the Rhizomes of Anemarrhena asphodeloides
- Authors
- Youn, Ui Joung; Lee, Ye Seul; Jeong, Hana; Lee, Jun; Nam, Joo-Won; Lee, Yoo Jin; Hwang, Eun Sook; Lee, Je-Hyun; Lee, Dongho; Kang, Sam Sik; Seo, Eun-Kyoung
- Issue Date
- 10월-2009
- Publisher
- AMER CHEMICAL SOC
- Citation
- JOURNAL OF NATURAL PRODUCTS, v.72, no.10, pp.1895 - 1898
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF NATURAL PRODUCTS
- Volume
- 72
- Number
- 10
- Start Page
- 1895
- End Page
- 1898
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/119228
- DOI
- 10.1021/np900397f
- ISSN
- 0163-3864
- Abstract
- Three new phenolic compounds, (E)-4'-demethyl-6-methyleucomin (1), anemarcoumarin A (2), and anemarchalconyn (3), were isolated from an ethyl acetate extract of the rhizomes of Anemarrhena asphodeloides, together with seven known compounds (4-10). The structures of the new compounds (1-3) were determined on the basis of spectroscopic data interpretation. Compound 3 exhibited a potent inhibitory effect against the differentiation of preadipocyte 3T3-L1 cells with an IC50 value of 5.3 mu M.
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