Association of serum n-6 and n-3 polyunsaturated fatty acids with lipids in 3 populations of middle-aged men
DC Field | Value | Language |
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dc.contributor.author | Motoyama, Kenneth R. | - |
dc.contributor.author | Curb, J. David | - |
dc.contributor.author | Kadowaki, Takashi | - |
dc.contributor.author | El-Saed, Aiman | - |
dc.contributor.author | Abbott, Robert D. | - |
dc.contributor.author | Okamura, Tomonori | - |
dc.contributor.author | Evans, Rhobert W. | - |
dc.contributor.author | Nakamura, Yasuyuki | - |
dc.contributor.author | Sutton-Tyrrell, Kim | - |
dc.contributor.author | Rodriquez, Beatriz L. | - |
dc.contributor.author | Kadota, Aya | - |
dc.contributor.author | Edmundowicz, Daniel | - |
dc.contributor.author | Willcox, Bradley J. | - |
dc.contributor.author | Choo, Jina | - |
dc.contributor.author | Katsumi, Nakata | - |
dc.contributor.author | Otake, Teruo | - |
dc.contributor.author | Kadowaki, Sayaka | - |
dc.contributor.author | Kuller, Lewis H. | - |
dc.contributor.author | Ueshima, Hirotusgu | - |
dc.contributor.author | Sekikawa, Akira | - |
dc.date.accessioned | 2021-09-08T15:37:15Z | - |
dc.date.available | 2021-09-08T15:37:15Z | - |
dc.date.created | 2021-06-10 | - |
dc.date.issued | 2009-07-01 | - |
dc.identifier.issn | 0002-9165 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/119688 | - |
dc.description.abstract | Background: The association of serum polyunsaturated fatty acids (PUFAs) with lipids in different populations is not known. Objective: Our aim was to examine the association of serum n-6 (omega-6) or n-3 (omega-3) PUFAs with triglycerides or HDL-cholesterol concentrations in 261 white, 285 Japanese, and 212 Japanese American men aged 40 49 y. Design: We used a population-based cross-sectional study. Of the original sample (n = 926), those taking lipid-lowering medications or who had diabetes (n = 168) were excluded. Serum fatty acids were analyzed by capillary gas-liquid chromatography. Multiple regression models as a function of tertile groups of each PUFA were used. Results: Serum n-6 PUFAs were significantly inversely associated with triglycerides across populations after adjustment for age, body mass index, pack-years of smoking, and ethanol consumption [beta = -0.39 (P < 0.001), -0.38 (P < 0.001), and -0.33 (P < 0.001) in whites, Japanese, and Japanese Americans, respectively]. Marine n-3 PUFAs were significantly inversely associated with triglycerides across populations [beta = -0.15 (P < 0.001), -0.22 (P < 0.001), and -0.13 (P < 0.001) in whites, Japanese, and Japanese Americans, respectively]. n-6 PUFAs were significantly positively associated with HDL cholesterol in whites (beta = 4.49, P < 0.001) and Japanese (beta = 3.73, P < 0.01). Marine n-3 PUFAs were significantly positively associated with HDL cholesterol in Japanese (beta = 2.15, P < 0.05), and eicosapentaenoic acid was significantly positively associated with HDL cholesterol in whites (beta = 2.68, P < 0.01). Conclusion: Serum n-6 and n-3 PUFAs are inversely associated with triglycerides across populations. Am J Clin Nutr 2009;90:49-55. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | OXFORD UNIV PRESS | - |
dc.subject | CORONARY-HEART-DISEASE | - |
dc.subject | ALPHA-LINOLENIC ACID | - |
dc.subject | DENSITY-LIPOPROTEIN CHOLESTEROL | - |
dc.subject | BLOOD-CELL MEMBRANES | - |
dc.subject | JAPANESE MEN | - |
dc.subject | CARDIOVASCULAR-DISEASE | - |
dc.subject | EICOSAPENTAENOIC ACID | - |
dc.subject | DIETARY FATS | - |
dc.subject | RISK-FACTOR | - |
dc.subject | WHITE MEN | - |
dc.title | Association of serum n-6 and n-3 polyunsaturated fatty acids with lipids in 3 populations of middle-aged men | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Choo, Jina | - |
dc.identifier.doi | 10.3945/ajcn.2008.26761 | - |
dc.identifier.scopusid | 2-s2.0-67649859459 | - |
dc.identifier.wosid | 000267373200008 | - |
dc.identifier.bibliographicCitation | AMERICAN JOURNAL OF CLINICAL NUTRITION, v.90, no.1, pp.49 - 55 | - |
dc.relation.isPartOf | AMERICAN JOURNAL OF CLINICAL NUTRITION | - |
dc.citation.title | AMERICAN JOURNAL OF CLINICAL NUTRITION | - |
dc.citation.volume | 90 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 49 | - |
dc.citation.endPage | 55 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Nutrition & Dietetics | - |
dc.relation.journalWebOfScienceCategory | Nutrition & Dietetics | - |
dc.subject.keywordPlus | CORONARY-HEART-DISEASE | - |
dc.subject.keywordPlus | ALPHA-LINOLENIC ACID | - |
dc.subject.keywordPlus | DENSITY-LIPOPROTEIN CHOLESTEROL | - |
dc.subject.keywordPlus | BLOOD-CELL MEMBRANES | - |
dc.subject.keywordPlus | JAPANESE MEN | - |
dc.subject.keywordPlus | CARDIOVASCULAR-DISEASE | - |
dc.subject.keywordPlus | EICOSAPENTAENOIC ACID | - |
dc.subject.keywordPlus | DIETARY FATS | - |
dc.subject.keywordPlus | RISK-FACTOR | - |
dc.subject.keywordPlus | WHITE MEN | - |
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