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Current Pharmacotherapy of Depression

Authors
Ham, Byung-JooJung, In-Kwa
Issue Date
May-2009
Publisher
KOREAN MEDICAL ASSOC
Keywords
Depression; Pharmacotherapy; Antidepressants
Citation
JOURNAL OF THE KOREAN MEDICAL ASSOCIATION, v.52, no.5, pp 518 - 524
Pages
7
Indexed
SCIE
SCOPUS
KCICANDI
Journal Title
JOURNAL OF THE KOREAN MEDICAL ASSOCIATION
Volume
52
Number
5
Start Page
518
End Page
524
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/120150
DOI
10.5124/jkma.2009.52.5.518
ISSN
1975-8456
2093-5951
Abstract
Currently, pharmacotherapy is the primary treatment modality for depression. Various classes of antidepressants have been developed and are widely used at present. Although the antidepressant effects of these drugs are thought to be similar, there are numerous differences between drugs in pharmacologic characteristics, side effects, and tolerabilities. Furthermore, 40 similar to 50% of patients may not respond sufficiently to the first-line antidepressants they take. As the response rates are substantially insufficient, and the side effects are not uncommon, the optimal treatment of antidepressants is somewhat difficult. Therefore, the clinicians treating depression should understand the characteristics of various antidepressants and also the optimal treatment strategy. In this review, we introduce various antidepressants and optimal treatment strategies for the treatment of depression.
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