CT-guided Radiofrequency Ablation for Hepatocellular Carcinomas That Were Undetectable at US: Therapeutic Effectiveness and Safety
- Authors
- Park, Beom Jin; Byun, Jae Ho; Jin, Yong Hyun; Won, Hyung Jin; Shin, Yong Moon; Kim, Kyoung Won; Park, Sang Joon; Kim, Pyo Nyun
- Issue Date
- 4월-2009
- Publisher
- ELSEVIER SCIENCE INC
- Citation
- JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, v.20, no.4, pp.490 - 499
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
- Volume
- 20
- Number
- 4
- Start Page
- 490
- End Page
- 499
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/120280
- DOI
- 10.1016/j.jvir.2009.01.004
- ISSN
- 1051-0443
- Abstract
- PURPOSE: To determine the therapeutic effectiveness and safety of computed tomography (CT)-guided radiofrequency (RF) ablation for hepatocelluar carcinomas (HCCs) that were undetectable at ultrasonography (US). MATERIALS AND METHODS: CT-guided RF ablation with use of internally cooled electrodes was performed in 66 patients with 97 HCCs (diameter range, 3-39 mm) in 78 sessions. Two radiologists retrospectively evaluated in consensus the presence or absence of local tumor progression as well as the complications at CT performed immediately after RF ablation and at 1-, 3-, 6-, and 12-month follow-up. The relationship between the occurrence of pneumothorax and the electrode length in the lung in patients treated with the transpulmonary approach was statistically evaluated with use of the Mann-Whitney test. RESULTS: The technical success rate of CT-guided RF ablation immediately after RF ablation was 97% (94 of 97 HCCs). The primary technique effectiveness rates of complete ablation 1, 3,6, and 12 months after RF ablation were 97% (94 of 97 HCCS), 94% (91 of 97 HCCs), 84% (81 of 96 HCCs), and 74% (66 of 89 HCCs), respectively. Major complications were observed in six of the 78 treatment sessions (7.7%). In five of these six sessions, pneumothorax developed immediately after RF ablation; the remaining complication was tumor seeding along the electrode tract. Self-limiting pneumothorax was observed in 12 of 38 sessions (32%) in which the transpulmonary approach was used. The electrode length in the lung was not statistically related to the occurrence of pneumothorax (P = .26). CONCLUSIONS: For HCCs that are undetectable at US, CT-guided RF ablation is effective and relatively safe.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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