Viral etiology and incidence associated with acute gastroenteritis in a 5-year survey in Gyeonggi province, South Korea
- Authors
- Huh, Jeong-Weon; Kim, Woon-Ho; Moon, Su-Gyeong; Lee, Jong-Bok; Lim, Young-Hee
- Issue Date
- Feb-2009
- Publisher
- ELSEVIER SCIENCE BV
- Keywords
- Viral gastroenteritis; Epidemiology; Phylogenetic analysis
- Citation
- JOURNAL OF CLINICAL VIROLOGY, v.44, no.2, pp.152 - 156
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF CLINICAL VIROLOGY
- Volume
- 44
- Number
- 2
- Start Page
- 152
- End Page
- 156
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/120620
- DOI
- 10.1016/j.jcv.2008.11.016
- ISSN
- 1386-6532
- Abstract
- Background: Acute gastroenteritis caused by viruses is one of the leading causes of childhood morbidity. Objective: The incidence and etiology of virus-associated gastroenteritis during 2001-2005 in Gyeonggi province, South Korea was determined. Study design: A total of 10,028 stool specimens were analyzed with enzyme immunoassay, reverse transcription-polymerase chain reaction, and nucleotide sequencing. Phylogenetic analysis of genotype sequences was performed for each of four commonly detected viral pathogens. Results: At least one viral agent was detected in 29.0% (2908 of 10,028) of the stool samples. Among these, rotavirus was most numerous (66.7%) followed by norovirus (12.6%), astrovirus (11.9%), and enteric adenovirus (2.6%). Mixed infections were identified in 180 cases (1.8%). Patients aged 1-5 years had the largest proportion 83.6% (2430 of 2908) of virus-positive stool specimens. Viral-mediated gastroenteritis was most common from December to May. The most prevalent strains of rotavirus, adenovirus, astrovirus, and norovirus were G1 type, type 41, G1 type, and GII-1 type, respectively. Conclusions: Our finding showed the diversity of viral causative agents of gastroenteritis and the prevalence of each gastroenteritis-associated viral genotype in South Korea. (C) 2008 Elsevier B.V. All rights reserved.
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