Antipathogenic Properties of Green Tea Polyphenol Epigallocatechin Gallate at Concentrations below the MIC against Enterohemorrhagic Escherichia coli O157:H7
DC Field | Value | Language |
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dc.contributor.author | Lee, Kang-Mu | - |
dc.contributor.author | Kim, Wan-Seok | - |
dc.contributor.author | Lim, Jeesun | - |
dc.contributor.author | Nam, Sunyoung | - |
dc.contributor.author | Youn, Min | - |
dc.contributor.author | Nam, Seong-Won | - |
dc.contributor.author | Kim, Younghoon | - |
dc.contributor.author | Kim, Sae-Hun | - |
dc.contributor.author | Park, Woojun | - |
dc.contributor.author | Park, Sungsu | - |
dc.date.accessioned | 2021-09-08T20:15:26Z | - |
dc.date.available | 2021-09-08T20:15:26Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2009-02 | - |
dc.identifier.issn | 0362-028X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/120674 | - |
dc.description.abstract | The inhibitory effects of green tea polyphenol epigallocatechin gallate (EGCG) on virulence phenotypes and gene expression regulated by quorum sensing (QS) in Escherichia coli O15TH7 were demonstrated at concentrations of 1 to 100 mu g/ml, which are lower than the MIC (539 +/- 22 mu g/ml). At 25 mu g/ml, the growth rate was not affected, but autoinducer 2 concentration, biofilm formation, and swarm motility decreased to 13.2, 11.8, and 50%, respectively. Survival at 5 days of nematodes (Caenorhabditis elegans) that were fed the pathogen without and with EGCG were 47.1 and 76%, respectively. Real-time PCR data indicated decreased transcriptional level in many quorum sensing-regulated virulence genes at 25 mu g/ml. Our results suggest that EGCG at concentrations below its MIC has significant antipathogenic effects against E. coli O157:H7. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | INT ASSOC FOOD PROTECTION | - |
dc.subject | RESISTANT STAPHYLOCOCCUS-AUREUS | - |
dc.subject | BIOFILM FORMATION | - |
dc.subject | CAENORHABDITIS-ELEGANS | - |
dc.subject | STREPTOCOCCUS-MUTANS | - |
dc.subject | CAMELLIA-SINENSIS | - |
dc.subject | O157-H7 | - |
dc.subject | SYSTEM | - |
dc.subject | VIRULENCE | - |
dc.subject | FLAGELLA | - |
dc.subject | ANTIBACTERIAL | - |
dc.title | Antipathogenic Properties of Green Tea Polyphenol Epigallocatechin Gallate at Concentrations below the MIC against Enterohemorrhagic Escherichia coli O157:H7 | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Sae-Hun | - |
dc.contributor.affiliatedAuthor | Park, Woojun | - |
dc.identifier.doi | 10.4315/0362-028X-72.2.325 | - |
dc.identifier.scopusid | 2-s2.0-60849099335 | - |
dc.identifier.wosid | 000263186700012 | - |
dc.identifier.bibliographicCitation | JOURNAL OF FOOD PROTECTION, v.72, no.2, pp.325 - 331 | - |
dc.relation.isPartOf | JOURNAL OF FOOD PROTECTION | - |
dc.citation.title | JOURNAL OF FOOD PROTECTION | - |
dc.citation.volume | 72 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 325 | - |
dc.citation.endPage | 331 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.subject.keywordPlus | RESISTANT STAPHYLOCOCCUS-AUREUS | - |
dc.subject.keywordPlus | BIOFILM FORMATION | - |
dc.subject.keywordPlus | CAENORHABDITIS-ELEGANS | - |
dc.subject.keywordPlus | STREPTOCOCCUS-MUTANS | - |
dc.subject.keywordPlus | CAMELLIA-SINENSIS | - |
dc.subject.keywordPlus | O157-H7 | - |
dc.subject.keywordPlus | SYSTEM | - |
dc.subject.keywordPlus | VIRULENCE | - |
dc.subject.keywordPlus | FLAGELLA | - |
dc.subject.keywordPlus | ANTIBACTERIAL | - |
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