Prenylated and Benzylated Flavonoids from the Fruits of Cudrania tricuspidata
- Authors
- Han, Xiang Hua; Hong, Seong Su; Jin, Qinghao; Li, Dayu; Kim, Hyun-Kyu; Lee, Jeongrai; Kwon, Suk Hyung; Lee, Dongho; Lee, Chong-Kil; Lee, Myung Koo; Hwang, Bang Yeon
- Issue Date
- Jan-2009
- Publisher
- AMER CHEMICAL SOC
- Citation
- JOURNAL OF NATURAL PRODUCTS, v.72, no.1, pp.164 - 167
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF NATURAL PRODUCTS
- Volume
- 72
- Number
- 1
- Start Page
- 164
- End Page
- 167
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/120848
- DOI
- 10.1021/np800418j
- ISSN
- 0163-3864
- Abstract
- Three new prenylated isoflavones, 5,7-dihydroxy-6-(2 ''-hydroxy-3 ''-methylbut-3 ''-enyl)-4'-methoxylisoflavone (1), 5,4'-dihydroxy-6-(3 ''-methylbut-2 ''-enyl)-2"'-(4"'-hydroxy-4"'-methylethyl)-3"'-methoxydihydrofurano [4"',5''';7,8]isoflavone (2), and 5,4'-dihydroxy-8-(3 ''-methylbut-2 ''-enyl)-2"'-(4"'-hydroxy-4"'-methylethyl)furano[4"',5''';6,7]isoflavone (3), a benzylated dihydroflavonol, 5,7,4'-trihydroxy-8-p-hydroxybenzyldihydroflavonol (4), and eight known flavonoids (5-12) were isolated from the fruits of Cudrania tricuspidata. The structures of these compounds were determined on the basis of MS and H-1 and C-13 NMR spectroscopic data, including 2D NMR experiments. Compounds 2, 3, 6, 7, 8, 10, 11, and 12 inhibited LPS-induced nitric oxide production, with IC50 values of 11.8-41.8 mu M.
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Collections - Graduate School > Department of Plant Biotechnology > 1. Journal Articles
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