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Bioassay-guided isolation of antiplasmodial anacardic acids derivatives from the whole plants of Viola websteri Hemsl

Authors
Lee, Sung JaePark, Won-HwanMoon, Hyung-In
Issue Date
Jan-2009
Publisher
SPRINGER
Citation
PARASITOLOGY RESEARCH, v.104, no.2, pp.463 - 466
Indexed
SCIE
SCOPUS
Journal Title
PARASITOLOGY RESEARCH
Volume
104
Number
2
Start Page
463
End Page
466
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/120880
DOI
10.1007/s00436-008-1205-z
ISSN
0932-0113
Abstract
The petroleum ether extract of Viola websteri Hemsl. (Violaceae) was investigated for its activity against chloroquine-sensitive strains of Plasmodium falciparum using the parasite lactate dehydrogenase assay method. The main antiplasmodial principles, 6-(8'Z-pentadecenyl)-salicylic acid (1) and 6-(8'Z, 11'Z, 14'Z-heptadecatrienyl)-salicylic acid (2), have been isolated from V. websteri for the first time. This is the first report on the antiplasmodial activity of the compounds from V. websteri.
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