Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

수영 운동이 외상성 뇌손상 유발 흰쥐에서의 c-Fos 발현에 미치는 영향The effect of swimming exercise on traumatic brain injury-induced c-Fos expression in rats

Other Titles
The effect of swimming exercise on traumatic brain injury-induced c-Fos expression in rats
Authors
김보균윤성진김승희서진희김대영성윤희김창주신말순윤진환이희혁
Issue Date
2009
Publisher
한국체육과학회
Keywords
traumatic brain injury; c-Fos exepression; exercise; paraventricular nucleus (PVN); ventrolateral periaqueductal gray (vlPAG); traumatic brain injury; c-Fos exepression; exercise; paraventricular nucleus (PVN); ventrolateral periaqueductal gray (vlPAG)
Citation
한국체육과학회지, v.18, no.1, pp.871 - 880
Indexed
KCI
OTHER
Journal Title
한국체육과학회지
Volume
18
Number
1
Start Page
871
End Page
880
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/121732
ISSN
1226-0258
Abstract
Traumatic brain injury is known to cause severe neurological damage and has a high mortality rate. c-Fos expression is recognized as a marker of increased neuronal activity, however, excessive c-Fos expression represents apoptotic neuronal cell death. In the present study, the effect of swimming exercise on traumatic brain injury-induced c-Fos expression in rats was investigated by c-Fos immunohistochemistry. The rats were divided into 3 groups: the sham-operation group, the traumatic brain injury-induction group, and the traumatic brain injury-induction and swimming exercise group. The animals in the exercise group were forced to swim for 30 min once a day during 14 consecutive days. The present results showed that traumatic brain injury enhanced the number of c-Fos-positive cells in the paraventricular nucleus (PVN) and ventrolateral periaqueductal gray (vlPAG) regions and that swimming exercise significantly suppressed the traumatic brain injury-induced c-Fos expression. In the traumatic brain injury rats, swimming exercise exerted inhibitory effect on the c-Fos exepression in the PVN and vlPAG regions. Based on the present results, it can be suggested that swimming exercise has a neuroprotective against traumatic brain injury by suppressing c-Fos expression.
Files in This Item
There are no files associated with this item.
Appears in
Collections
College of Education > Department of Physical Education > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher YOON, Sung Jin photo

YOON, Sung Jin
College of Education (Department of Physical Education)
Read more

Altmetrics

Total Views & Downloads

BROWSE