Effects of fruits and stems of opuntia ficus-indica on blood glucose and lipid metabolism in streptozotocin-induced diabetic rats
DC Field | Value | Language |
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dc.contributor.author | Yoon, J.A. | - |
dc.contributor.author | Son, Y.-S. | - |
dc.date.accessioned | 2021-09-09T00:28:36Z | - |
dc.date.available | 2021-09-09T00:28:36Z | - |
dc.date.created | 2021-06-17 | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1226-3311 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/121909 | - |
dc.description.abstract | This study was conducted to examine the effects of fruits and stems of Opuntia ficus-indica var. saboten Makino on water intake, feed intake, body weight, blood glucose level and glucose tolerance in streptozotocin (STZ)-induced diabetic rats. Forty Sprague-Dawley male rats were divided into non-diabetic control (NC), diabetic control (DC), 8% Opuntia fruit (DOF), 5% Opuntia stem (DO-5) and 10% Opuntia stem (DO-10) groups. Fruits and stems of Opuntia ficus-indica were freeze-dried and ground before use in the experiment. Animals were fed experimental diet for 3 weeks. DOF, DO-5 and DO-10 groups showed lower water and feed intake as well as less body weight loss than DC group. The fasting blood glucose levels were 100 mg/dL for NC and 379 mg/dL for DC. Fasting glucose level of DOF was a significantly low level of 28% (p<0.05), whereas DO-5 and DO-10 had a decrease of 5% and 9% compared to DC. As for the glucose tolerance test, the highest blood glucose levels for NC and DC-10 group were observed at 30 minutes after glucose injection while those of DOF and DO-5 groups were after 60 minutes. DOF and DO-5 plasma insulin level improved. Plasma total cholesterol, triglyceride, non-esterified fatty acid (NEFA) and LDL-cholesterol concentrations were also lower in DOF, DO-5 and DO-10 groups, although HDL-cholesterol level was only slightly affected by experimental diets compared to DC. These results suggest that the feeding of Opuntia ficus-indica fruits and stems improved blood glucose and lipid metabolism in STZ-induced diabetic rats. | - |
dc.language | Korean | - |
dc.language.iso | ko | - |
dc.subject | Animalia | - |
dc.subject | Opuntia | - |
dc.subject | Opuntia ficus-indica | - |
dc.subject | Rattus | - |
dc.title | Effects of fruits and stems of opuntia ficus-indica on blood glucose and lipid metabolism in streptozotocin-induced diabetic rats | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Son, Y.-S. | - |
dc.identifier.doi | 10.3746/jkfn.2009.38.2.146 | - |
dc.identifier.scopusid | 2-s2.0-68949142742 | - |
dc.identifier.bibliographicCitation | Journal of the Korean Society of Food Science and Nutrition, v.38, no.2, pp.146 - 153 | - |
dc.relation.isPartOf | Journal of the Korean Society of Food Science and Nutrition | - |
dc.citation.title | Journal of the Korean Society of Food Science and Nutrition | - |
dc.citation.volume | 38 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 146 | - |
dc.citation.endPage | 153 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001319058 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordPlus | Animalia | - |
dc.subject.keywordPlus | Opuntia | - |
dc.subject.keywordPlus | Opuntia ficus-indica | - |
dc.subject.keywordPlus | Rattus | - |
dc.subject.keywordAuthor | Blood glucose | - |
dc.subject.keywordAuthor | Cholesterol | - |
dc.subject.keywordAuthor | Insulin | - |
dc.subject.keywordAuthor | Opuntia ficus-indica | - |
dc.subject.keywordAuthor | Streptozotocin | - |
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