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Antimalarial activity of a new stilbene glycoside from Parthenocissus tricuspidata in mice
- Authors
- Park, Won-Hwan; Lee, Sung-Jae; Moon, Hyung-In
- Issue Date
- 9월-2008
- Publisher
- AMER SOC MICROBIOLOGY
- Citation
- ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, v.52, no.9, pp.3451 - 3453
- Indexed
- SCIE
SCOPUS
- Journal Title
- ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Volume
- 52
- Number
- 9
- Start Page
- 3451
- End Page
- 3453
- ISSN
- 0066-4804
- Abstract
- A novel stilbene glycoside [piceid-(1 -> 6)-beta-D-glucopyranoside; PBG] from Parthenocissus tricuspidata was tested in vivo against Plasmodium berghei. PBG exhibited significant blood schizontocidal activity in a 4-day early infection, a repository evaluation, and an established infection, with a significant mean survival time comparable to that obtained with the standard drug, chloroquine (5 mg . kg(-1) . day(-1)).
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