Interactome analysis of yeast glutathione peroxidase 3
DC Field | Value | Language |
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dc.contributor.author | Lee, Phil Young | - |
dc.contributor.author | Bae, Kwang-Hee | - |
dc.contributor.author | Kho, Chang Won | - |
dc.contributor.author | Kang, Sunghyun | - |
dc.contributor.author | Lee, Do Hee | - |
dc.contributor.author | Cho, Sayeon | - |
dc.contributor.author | Kang, Seongman | - |
dc.contributor.author | Lee, Sang Chul | - |
dc.contributor.author | Park, Byoung Chul | - |
dc.contributor.author | Park, Sung Goo | - |
dc.date.accessioned | 2021-09-09T05:31:51Z | - |
dc.date.available | 2021-09-09T05:31:51Z | - |
dc.date.created | 2021-06-10 | - |
dc.date.issued | 2008-08 | - |
dc.identifier.issn | 1017-7825 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/122906 | - |
dc.description.abstract | Oxidative stress damages all cellular constituents, and therefore, cell has to possess various defense mechanisms to cope. Saccharomyces cerevisiae, widely used as a model organism for studying cellular responses to oxidative stress, contains three glutathione peroxidase (Gpx) proteins. Among them, Gpx3 plays a major defense role against oxidative stress in V. cerevisiae. In this study, in order to identify the new interaction proteins of Gpx3, we carried out two-dimensional gel electrophoresis after immunoprecipitation (IP-2DE), and MALDI-TOF mass spectrometry. The results showed that several proteins including protein disulfide isomerase, glutaredoxin 2, and SSY protein 3 specifically interact with Gpx3. These findings led us to suggest the possibility that Gpx3, known as a redox sensor and ROS scavenger, has another functional role by interacting with several proteins with various cellular functions. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC MICROBIOLOGY & BIOTECHNOLOGY | - |
dc.subject | PROTEIN DISULFIDE-ISOMERASE | - |
dc.subject | INDUCED OXIDATIVE STRESS | - |
dc.subject | NEURONAL CELL-DEATH | - |
dc.subject | SACCHAROMYCES-CEREVISIAE | - |
dc.subject | PEROXIDASE | - |
dc.subject | ACTIVATION | - |
dc.subject | STATE | - |
dc.subject | H2O2 | - |
dc.title | Interactome analysis of yeast glutathione peroxidase 3 | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kang, Seongman | - |
dc.identifier.scopusid | 2-s2.0-56749166093 | - |
dc.identifier.wosid | 000258787500003 | - |
dc.identifier.bibliographicCitation | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.18, no.8, pp.1364 - 1367 | - |
dc.relation.isPartOf | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY | - |
dc.citation.title | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY | - |
dc.citation.volume | 18 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 1364 | - |
dc.citation.endPage | 1367 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001274728 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalResearchArea | Microbiology | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Microbiology | - |
dc.subject.keywordPlus | PROTEIN DISULFIDE-ISOMERASE | - |
dc.subject.keywordPlus | INDUCED OXIDATIVE STRESS | - |
dc.subject.keywordPlus | NEURONAL CELL-DEATH | - |
dc.subject.keywordPlus | SACCHAROMYCES-CEREVISIAE | - |
dc.subject.keywordPlus | PEROXIDASE | - |
dc.subject.keywordPlus | ACTIVATION | - |
dc.subject.keywordPlus | STATE | - |
dc.subject.keywordPlus | H2O2 | - |
dc.subject.keywordAuthor | glutathione peroxidase 3 | - |
dc.subject.keywordAuthor | IP-2DE | - |
dc.subject.keywordAuthor | oxidative stress | - |
dc.subject.keywordAuthor | ROS | - |
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