Selective enrichment of cysteine-containing peptides using SPDP-Functionalized superparamagnetic Fe3O4@SiO2 nanoparticles: Application to comprehensive proteomic profiling
- Authors
- Palani, Arudra; Lee, Je-Sun; Huh, Jiyoung; Kim, Minsik; Lee, Yeon-Ji; Chang, Jeong Ho; Lee, Kwangyeol; Lee, Sang-Won
- Issue Date
- 8월-2008
- Publisher
- AMER CHEMICAL SOC
- Keywords
- superparamagnetic nanoparticle; surface modification; cysteine containing peptide enrichment; tandem mass spectrometry; proteomics
- Citation
- JOURNAL OF PROTEOME RESEARCH, v.7, no.8, pp.3591 - 3596
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF PROTEOME RESEARCH
- Volume
- 7
- Number
- 8
- Start Page
- 3591
- End Page
- 3596
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/122951
- DOI
- 10.1021/pr800067x
- ISSN
- 1535-3893
- Abstract
- Superparamagnetic Fe3O4@SiO2 core-shell nanoparticles (ca. 30 nm diameter), which are surface-modified with a thiol-specific functional group, exhibit superb capturing efficiency toward cysteinyl peptides without contamination from nonspecifically interacting peptides, as clearly evidenced through LC/MS/MS analysis.
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Collections - College of Science > Department of Chemistry > 1. Journal Articles
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