Identification and characterization of new microRNAs from pig
- Authors
- Kim, Jung; Cho, Ik Sang; Hong, Jae Sang; Choi, Young Ki; Kim, Hyunggee; Lee, Young Sik
- Issue Date
- Aug-2008
- Publisher
- SPRINGER
- Citation
- MAMMALIAN GENOME, v.19, no.7-8, pp.570 - 580
- Indexed
- SCIE
SCOPUS
- Journal Title
- MAMMALIAN GENOME
- Volume
- 19
- Number
- 7-8
- Start Page
- 570
- End Page
- 580
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/122984
- DOI
- 10.1007/s00335-008-9111-3
- ISSN
- 0938-8990
- Abstract
- MicroRNAs (miRNAs) are small regulatory RNAs that direct the posttranscriptional repression of cognate messenger RNAs. Despite increasing evidence for diverse roles of miRNAs in biological processes, little is known about miRNAs in pig. We describe the first experimental identification of porcine miRNAs by sequence analysis of a cDNA library of small RNAs from porcine fibroblast cells. We identified 25 distinct porcine miRNAs, of which 19 are previously unreported, and define 14 new miRNA families in pig. Most of the cloned miRNAs are expressed ubiquitously in all porcine tissues examined, whereas some miRNAs are expressed preferentially in specific tissues. Our results enrich the porcine miRNA database and provide useful information for investigating biological functions of miRNAs in pig.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - Graduate School > Department of Biotechnology > 1. Journal Articles
- College of Life Sciences and Biotechnology > Division of Biotechnology > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.