The influence of age on the treadmill exercise-induced c-Fos expression in the hippocampus of rats
- Authors
- Kim, SH; Kim, H; Kim, SS; Shin, MS; Chang, HK; Lee, TH; Jang, MH; Shin, MC; Lee, HH; Kim, YP; Kim, CJ
- Issue Date
- 7월-2004
- Publisher
- WILEY
- Keywords
- c-Fos; treadmill exercise; age; hippocampus; immunohistochemistry
- Citation
- NEUROSCIENCE RESEARCH COMMUNICATIONS, v.35, no.1, pp.41 - 50
- Indexed
- SCIE
SCOPUS
- Journal Title
- NEUROSCIENCE RESEARCH COMMUNICATIONS
- Volume
- 35
- Number
- 1
- Start Page
- 41
- End Page
- 50
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/123605
- DOI
- 10.1002/nrc.20018
- ISSN
- 0893-6609
- Abstract
- c-Fos has been used as a neuronal activity marker. Here, we examined the influence of age on the treadmill running-induced c-Fos expression in rat hippocampus. Rats of exercise groups were forced to run on treadmill for 30 min once a day for 5 consecutive days. Without exercise, c-Fos expression was highest in 8-week old rats. Treadmill exercise significantly enhanced the c-Fos expression in the hippocampus of rats in all ages. In the CA region, the increase of the c-Fos expression by treadmill exercise was highest in 4-week old rats. In the dentate gyrus, the increase of the c-Fos expression by treadmill exercise was highest in 62-week old rats. The data show that age is an important factor for the regulation of the c-Fos expression in the hippocampus and that the ability of the treadmill exercise enhancing the c-Fos expression is dependent on age status.
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Collections - College of Culture and Sports > Sport Science in Division of Global Sport Studies > 1. Journal Articles
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