Hyperthermia with magnetic nanowires for inactivating living cells
- Authors
- Choi, D. S.; Park, J.; Kim, S.; Gracias, D. H.; Cho, M. K.; Kim, Y. K.; Fung, A.; Lee, S. E.; Chen, Y.; Khanal, S.; Baral, S.; Kim, J. -H.
- Issue Date
- May-2008
- Publisher
- AMER SCIENTIFIC PUBLISHERS
- Keywords
- nanowire; hyperthermia; treatment of cancer; RF heating
- Citation
- JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, v.8, no.5, pp.2323 - 2327
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
- Volume
- 8
- Number
- 5
- Start Page
- 2323
- End Page
- 2327
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/123705
- DOI
- 10.1166/jnn.2008.273
- ISSN
- 1533-4880
- Abstract
- We describe a method to induce hyperthermia in cells, in-vitro, by remotely heating Ni nanowires (NWs) with radio frequency (RF) electromagnetic fields. Ni NWs were internalized by human embryonic kidney cells (HEK-293). Only cells proximal to NWs or with internalized NWs changed shape on exposure to RF fields indicative of cell death. The cell death occurs as a result of hyperthermia, since the RF field remotely heats the NWs as a result of magnetic hysteresis. This is the first demonstration of hyperthermia induced by NWs; since the NWs have anisotropic and strong magnetic moments, our experiments suggest the possibility of performing hyperthermia at lower field strengths in order to minimize damage to untargeted cells in applications such as the treatment of cancer.
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Collections - College of Engineering > Department of Materials Science and Engineering > 1. Journal Articles
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