Evolution of VX2 carcinoma in rabbit tibia: magnetic resonance imaging with pathologic correlation
DC Field | Value | Language |
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dc.contributor.author | Choi, Jung-Ah | - |
dc.contributor.author | Kang, Eun Young | - |
dc.contributor.author | Kim, Han Kyeorn | - |
dc.contributor.author | Song, In Chan | - |
dc.contributor.author | Kim, Young I. I. | - |
dc.contributor.author | Kang, Heung Sik | - |
dc.date.accessioned | 2021-09-09T10:40:58Z | - |
dc.date.available | 2021-09-09T10:40:58Z | - |
dc.date.created | 2021-06-10 | - |
dc.date.issued | 2008-03 | - |
dc.identifier.issn | 0899-7071 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/123959 | - |
dc.description.abstract | Objective: To evaluate the evolution of a metastatic bone tumor model with MRI-pathology correlation. Materials and Methods: VX2 carcinoma was implanted into the tibiae of 20 rabbits. The rabbits were divided into four groups of five (Groups I-IV). MRI was repeated at 1-week interval up to the fourth week, including sagittal T1-weighted image (T1WI), T2-weighted image (T2WI), gadolinium-enhanced fat-suppressed T1WI (GdT1WI), and diffusion-weighted image (DWI). Each group was sacrificed after the imaging, then histological examination for the tibiae with an implanted tumor was performed and MRI-pathologic correlation was done. Results: On MRI-pathology correlation, the corresponding findings were as follows; low SI on T1WI, T2WI-tumor cells, fibrosis (I week); central low SI on T1WI, T2WI, GdT1WI -tumor cells with fibrosis and necrosis; peripheral high SI on T2WI, DWI, GdT1WI-edema, fibrosis (2 weeks); heterogeneous SI with central low SI on T2WI, DWI-tumor cell nests with extensive necrosis, fibrosis; high SI on T2WI along periosteum-periosteal reaction; high SI around low SI and in bone marrow on T2WI, DWI, GdT1WI-edema, fibrosis; low SI on T1WI in surrounding bone marrow-tumor extension (3-4 weeks). Conclusion: The evolution of VX2 carcinoma model was well depicted on MR imaging. Necrosis and extent of tumor were best depicted on enhanced, fat-suppressed T1-weighted images. Heterogeneity of the tumor, peripheral edema, and fibrosis were represented well on T2-weighted images. Diffusion-weighted imaging could have a role in depicting necrosis in the evaluation of bone tumor. (C) 2008 Elsevier Inc. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.subject | PREOPERATIVE CHEMOTHERAPY | - |
dc.subject | MUSCULOSKELETAL NEOPLASMS | - |
dc.subject | VX-2 CARCINOMA | - |
dc.subject | MR-IMAGES | - |
dc.subject | TUMOR | - |
dc.subject | DIFFUSION | - |
dc.subject | BONE | - |
dc.subject | PERFUSION | - |
dc.subject | SARCOMA | - |
dc.subject | LESIONS | - |
dc.title | Evolution of VX2 carcinoma in rabbit tibia: magnetic resonance imaging with pathologic correlation | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kang, Eun Young | - |
dc.contributor.affiliatedAuthor | Kim, Han Kyeorn | - |
dc.identifier.doi | 10.1016/j.clinimag.2007.08.021 | - |
dc.identifier.scopusid | 2-s2.0-39649104811 | - |
dc.identifier.wosid | 000254023200008 | - |
dc.identifier.bibliographicCitation | CLINICAL IMAGING, v.32, no.2, pp.128 - 135 | - |
dc.relation.isPartOf | CLINICAL IMAGING | - |
dc.citation.title | CLINICAL IMAGING | - |
dc.citation.volume | 32 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 128 | - |
dc.citation.endPage | 135 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | PREOPERATIVE CHEMOTHERAPY | - |
dc.subject.keywordPlus | MUSCULOSKELETAL NEOPLASMS | - |
dc.subject.keywordPlus | VX-2 CARCINOMA | - |
dc.subject.keywordPlus | MR-IMAGES | - |
dc.subject.keywordPlus | TUMOR | - |
dc.subject.keywordPlus | DIFFUSION | - |
dc.subject.keywordPlus | BONE | - |
dc.subject.keywordPlus | PERFUSION | - |
dc.subject.keywordPlus | SARCOMA | - |
dc.subject.keywordPlus | LESIONS | - |
dc.subject.keywordAuthor | bone neoplasms, diagnosis | - |
dc.subject.keywordAuthor | bone neoplasms, MR | - |
dc.subject.keywordAuthor | magnetic resonance (MR), contrast enhancement | - |
dc.subject.keywordAuthor | magnetic resonance (MR), experimental | - |
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