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당뇨발 환자의 창상치유예측을 위한 혈중 교원질 농도Serum Collagen Level as a Predictor of Healing Wounds in Diabetic Foot Patients

Other Titles
Serum Collagen Level as a Predictor of Healing Wounds in Diabetic Foot Patients
Authors
구자혜한승규김우경
Issue Date
2008
Publisher
대한성형외과학회
Keywords
Diabetic foot; Wound healing; Serum collagen level; Diabetic foot; Wound healing; Serum collagen level
Citation
Archives of Plastic Surgery, v.35, no.5, pp.491 - 494
Indexed
KCI
Journal Title
Archives of Plastic Surgery
Volume
35
Number
5
Start Page
491
End Page
494
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/124247
ISSN
2234-6163
Abstract
Purpose: When deciding a treatment plan in diabetic foot ulcer patients, predicting a possibility of healing wounds is important since not a few patients have poor general condition to get successful wound healing. This study was planned to find out if a serum collagen level can be used as a predictor for healing wounds in diabetic foot patients. Methods: Fifty-seven patients, who visited our clinic from January to June, 2007 for treatment of diabetic foot ulcers, were included in this study. Serum levels of type I collagen were checked using carboxy terminal type I propeptide kits. Simultaneously serum levels of vitamin C and iron, cofactors of collagen synthesis, were checked. The patients were divided into two groups; a group of successfully healed wounds and the other of unhealed wounds. Serum levels of the parameters were compared between the 2 groups. Results: The serum level of collagen was 197.65± 86.26ng/ml in a healed group and 87.91±28.76ng/ml in the unhealed group(p<0.05). The serum iron and vitamin C levels were did not show significant differences. Conclusion: The serum collagen level may predict healing or nonhealing wounds in diabetic foot ulcers.
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