당뇨발 환자의 창상치유예측을 위한 혈중 교원질 농도Serum Collagen Level as a Predictor of Healing Wounds in Diabetic Foot Patients
- Other Titles
- Serum Collagen Level as a Predictor of Healing Wounds in Diabetic Foot Patients
- Authors
- 구자혜; 한승규; 김우경
- Issue Date
- 2008
- Publisher
- 대한성형외과학회
- Keywords
- Diabetic foot; Wound healing; Serum collagen level; Diabetic foot; Wound healing; Serum collagen level
- Citation
- Archives of Plastic Surgery, v.35, no.5, pp.491 - 494
- Indexed
- KCI
- Journal Title
- Archives of Plastic Surgery
- Volume
- 35
- Number
- 5
- Start Page
- 491
- End Page
- 494
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/124247
- ISSN
- 2234-6163
- Abstract
- Purpose: When deciding a treatment plan in diabetic foot ulcer patients, predicting a possibility of healing wounds is important since not a few patients have poor general condition to get successful wound healing. This study was planned to find out if a serum collagen level can be used as a predictor for healing wounds in diabetic foot patients.
Methods: Fifty-seven patients, who visited our clinic from January to June, 2007 for treatment of diabetic foot ulcers, were included in this study. Serum levels of type I collagen were checked using carboxy terminal type I propeptide kits. Simultaneously serum levels of vitamin C and iron, cofactors of collagen synthesis, were checked. The patients were divided into two groups; a group of successfully healed wounds and the other of unhealed wounds. Serum levels of the parameters were compared between the 2 groups.
Results: The serum level of collagen was 197.65± 86.26ng/ml in a healed group and 87.91±28.76ng/ml in the unhealed group(p<0.05). The serum iron and vitamin C levels were did not show significant differences.
Conclusion: The serum collagen level may predict healing or nonhealing wounds in diabetic foot ulcers.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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