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Effects of hair dyeing on DNA damage in human lymphocytes

Authors
Cho, JAOh, ELee, ESul, D
Issue Date
11월-2003
Publisher
WILEY
Keywords
comet assay; lymphocytes; hair; dye
Citation
JOURNAL OF OCCUPATIONAL HEALTH, v.45, no.6, pp.376 - 381
Indexed
SCIE
SCOPUS
Journal Title
JOURNAL OF OCCUPATIONAL HEALTH
Volume
45
Number
6
Start Page
376
End Page
381
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/124347
DOI
10.1539/joh.45.376
ISSN
1341-9145
Abstract
Effects of Hair Dyeing on DNA Damage in Human Lymphocytes: Jin-A CHOA, et al. Department of Beauty Arts, Seokyeong University, Korea-Comet assays were carried out to evaluate DNA damage in human lymphocytes from 20 volunteers before and after hair dyeing. DNA damage in lymphocytes was found to be slightly higher in volunteers after hair dyeing. Tail moments before and after hair dyeing were 1.47 +/- 0.41 and 1.75 +/- 0.29 respectively (p < 0.0008). DNA damage in lymphocytes showed significant difference with treatment and heating time. The tail moments after 15 min of treatment time before and after hair dyeing were 1.44 +/- 0.22 and 1.85 +/- 0.36, respectively (p = 0.0004) and the corresponding tail moments in 20 min of heating time before and after were 1.37 +/- 0.15 and 1.78 +/- 0.34 (p = 0.0002). In conclusion, we found that an acute exposure of hair dyes with heating caused DNA damages in peripheral lymphocytes and that this damage had significant association with treatment and heating time.
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