비장적출술로 호전된 불응성 혈전성 혈소판감소성 자반증 1예
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이재원 | - |
dc.contributor.author | 김선철 | - |
dc.contributor.author | 오세원 | - |
dc.contributor.author | 차진주 | - |
dc.contributor.author | 김혜원 | - |
dc.contributor.author | 부창수 | - |
dc.contributor.author | 이지은 | - |
dc.contributor.author | 권영주 | - |
dc.contributor.author | 표희정 | - |
dc.date.accessioned | 2021-09-09T13:46:13Z | - |
dc.date.available | 2021-09-09T13:46:13Z | - |
dc.date.created | 2021-06-17 | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 2211-9132 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/124689 | - |
dc.description.abstract | The introduction of plasma exchange has significantly improved the outcome of thrombotic thrombocytopenic purpura (TTP) and the survival rate was increased from 10 to 80-90%. TTP refractory to plasma exchange therapy, however, is still a therapeutic challenge. We describe here a patient who partially responded to plasma exchange therapy, but remained dependent on plasma infusions. To discontinue plasma therapy, several attempts using agents such as rituximab, vincristine, and cyclosporine A had been tried, but all failed. After splenectomy, serum LDH and blood platelet count were normalized. Plasmapheresis were we able to discontinue after 2 weeks of splenectomy. Steroid and cyclosporine were tapered off after 3 months and 5 months after splenectomy respectively, and the patient has been staying in remission ever since. We suggest that splenectomy is a worthwhile treatment option in patients with refractory TTP. | - |
dc.language | Korean | - |
dc.language.iso | ko | - |
dc.publisher | 대한신장학회 | - |
dc.title | 비장적출술로 호전된 불응성 혈전성 혈소판감소성 자반증 1예 | - |
dc.title.alternative | A Case of Splenectomy in a Patient with Refractory Thrombotic Thrombocytopenic Purpura | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | 차진주 | - |
dc.contributor.affiliatedAuthor | 권영주 | - |
dc.contributor.affiliatedAuthor | 표희정 | - |
dc.identifier.bibliographicCitation | Kidney Research and Clinical Practice, v.27, no.2, pp.243 - 247 | - |
dc.relation.isPartOf | Kidney Research and Clinical Practice | - |
dc.citation.title | Kidney Research and Clinical Practice | - |
dc.citation.volume | 27 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 243 | - |
dc.citation.endPage | 247 | - |
dc.type.rims | ART | - |
dc.identifier.kciid | ART001243526 | - |
dc.description.journalClass | 2 | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordAuthor | Thrombotic thrombocytopenic purpura | - |
dc.subject.keywordAuthor | Splenectomy | - |
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