A Matched-cohort Comparison of Laparoscopic Renal Cryoablation using Ultra-thin Cryoprobes with Open Partial Nephrectomy for the Treatment of Small Renal Cell CarcinomaA Matched-cohort Comparison of Laparoscopic Renal Cryoablation using Ultra-thin Cryoprobes with Open Partial Nephrectomy for the Treatment of Small Renal Cell Carcinoma
- Other Titles
- A Matched-cohort Comparison of Laparoscopic Renal Cryoablation using Ultra-thin Cryoprobes with Open Partial Nephrectomy for the Treatment of Small Renal Cell Carcinoma
- Authors
- 고영일; 박홍석; 문두건; 이정구; 김제종; 윤덕기; 강석호; 천준
- Issue Date
- 2008
- Publisher
- 대한암학회
- Keywords
- Cryosurgery; Partial nephrectomy; Renal cell carcinoma
- Citation
- Cancer Research and Treatment, v.40, no.4, pp.184 - 189
- Indexed
- KCI
- Journal Title
- Cancer Research and Treatment
- Volume
- 40
- Number
- 4
- Start Page
- 184
- End Page
- 189
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/124742
- ISSN
- 1598-2998
- Abstract
- Purpose: To evaluate the feasibility and efficacy of performing
laparoscopic renal cryoablation (LRC) for the
treatment of RCC, as compared with open partial nephrectomy
(OPN), which is the established NSS.
Materials and Methods: From April 2004, among the patients
who underwent LRC with a 1.47 mm cryoprobe, we
enrolled 20 patients who were pathologically confirmed
as having RCC with a tumor size smaller than 4 cm.
These patients were matched with a group of 20 patients,
who were selected based on the pre-operative characteristics
of the tumor and those of the patients, from a
pre-existing database of the patients who underwent
OPN during the same period.
Results: The mean age and tumor size were 56.3±11.5
years and 2.4±1.7 cm in the LRC group, and 57.6±10.9
years and 2.2±1.1 cm in the OPN group. The two
groups were similar for their age, gender, BMI, ASA, the
tumor characteristics and the indications for operation.
While the pathologic results and the operation time showed similarity, the EBL (98±87 ml vs 351±147 ml, respectively,
p=0.001), the transfusion rate (10% vs 40%, respectively,
p=0.03) and the hospital stay (4.2±1.5 days vs
8.2±2.4 days, respectively, p=0.005) were significantly
less in the LRC group. Major complications did not occur
in the LRC group, but in the OPN group, one patient experienced
urine leakage and one patient had a perirenal
hematoma. During the mean follow up of 27.3±10.8
months and 28.7±14.9 months for each group, respectively,
all the patients remained disease- free with no
evidence of local recurrence or metastases.
Conclusions: LRC using ultra-thin cryoprobes for the
treatment of small RCC showed similar effective oncologic
results with the merits of minimal invasiveness, as
compared with OPN, during the intermediate term follow
up.
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