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A case of ticlopidine induced acute cholestatic hepatitis and pure red cell aplasia
- Authors
- Lee, J.Y.; Park, E.B.; Ahn, J.H.; Suh, S.J.; Jung, Y.K.; Kim, J.H.; Shin, B.K.; Yang, J.H.; Yeon, J.E.; Byun, K.S.
- Issue Date
- 2008
- Keywords
- Ticlopidine; Pure red cell aplasia; Hepatitis; Drug-Induced; Adverse effect; 티클로피딘; 진정적혈구계무형성증; 담즙정체간염; 부작용; Ticlopidine; Pure red cell aplasia; Hepatitis; Drug-Induced; Adverse effect
- Citation
- The Korean journal of hepatology, v.14, no.1, pp.102 - 107
- Indexed
- SCOPUS
KCI
- Journal Title
- The Korean journal of hepatology
- Volume
- 14
- Number
- 1
- Start Page
- 102
- End Page
- 107
- ISSN
- 1738-222X
- Abstract
- Ticlopidine inhibits platelet aggregation and provides beneficial secondary prevention of cerebrovascular and coronary artery disease. Frequently reported adverse effects of ticlopidine include diarrhea, nausea, and rash. However, to our knowledge, there are only a few published reports of the simultaneous occurrence of cholestatic hepatitis and pure red cell aplasia. Here we report a patient with simultaneous severe cholestatic hepatitis and pure red cell aplasia associated with ticlopidine. Although these adverse effects are rare, periodic hematological and liver function tests are recommended after starting ticlopidine.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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