Serum adiponectin, interleukin-10 levels and inflammatory markers in the metabolic syndrome
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Choi, K. M. | - |
dc.contributor.author | Ryu, O. H. | - |
dc.contributor.author | Lee, K. W. | - |
dc.contributor.author | Kim, H. Y. | - |
dc.contributor.author | Seo, J. A. | - |
dc.contributor.author | Kim, S. G. | - |
dc.contributor.author | Kim, N. H. | - |
dc.contributor.author | Choi, D. S. | - |
dc.contributor.author | Baik, S. H. | - |
dc.date.accessioned | 2021-09-09T17:28:19Z | - |
dc.date.available | 2021-09-09T17:28:19Z | - |
dc.date.created | 2021-06-10 | - |
dc.date.issued | 2007-02 | - |
dc.identifier.issn | 0168-8227 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/125820 | - |
dc.description.abstract | We examined the association between interleukin-10 (IL-10), adiponectin levels and inflammatory markers such as interleukin-6 (IL-6) and high-sensitive C-reactive protein (hsCRP). Furthermore, the association of these anti-/pro-inflammatory cytokine levels with the metabolic syndrome was investigated. The study subjects were composed of 312 Korean individuals without diabetes. Serum adiponectin level was associated with hsCRP (r = -0.21, P < 0.001), IL-6 (r = -0. 13, P < 0.05) and IL-10 (r = -0.22, P < 0.001) levels. Subjects without the metabolic syndrome showed higher adiponectin (17.03 mu g/ml versus 13.85 mu g/ml, P < 0.001) and IL-10 (4.74 pg/ml versus 4.34 pg/ml, P = 0.014) levels, and lower serum hsCRP (0.38 mu g/ml versus 0.66 mu g/ ml, P = 0.001) and IL-6 (0.94 pg/ml versus 1.32 pg/ml, P = 0.009) levels compared to those with the metabolic syndrome. In multiple logistic regression analysis, the metabolic syndrome was associated with sex, age, waist circumference, systolic blood pressure, HDL cholesterol, triglyceride, fasting blood glucose and interleukin-10. Furthermore, serum adiponectin levels are associated with serum hsCRP, IL-6 and IL-10 levels. These results suggest that adiponectin might be associated with the metabolic syndrome through regulation of pro-/anti-inflammatory cytokines. (c) 2006 Elsevier Ireland Ltd. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER IRELAND LTD | - |
dc.subject | C-REACTIVE PROTEIN | - |
dc.subject | INSULIN-RESISTANCE | - |
dc.subject | CARDIOVASCULAR-DISEASE | - |
dc.subject | MECHANISMS | - |
dc.subject | ATHEROSCLEROSIS | - |
dc.subject | ASSOCIATION | - |
dc.subject | MORTALITY | - |
dc.subject | MICE | - |
dc.title | Serum adiponectin, interleukin-10 levels and inflammatory markers in the metabolic syndrome | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Seo, J. A. | - |
dc.identifier.doi | 10.1016/j.diabres.2006.06.019 | - |
dc.identifier.scopusid | 2-s2.0-33845447909 | - |
dc.identifier.wosid | 000243668600016 | - |
dc.identifier.bibliographicCitation | DIABETES RESEARCH AND CLINICAL PRACTICE, v.75, no.2, pp.235 - 240 | - |
dc.relation.isPartOf | DIABETES RESEARCH AND CLINICAL PRACTICE | - |
dc.citation.title | DIABETES RESEARCH AND CLINICAL PRACTICE | - |
dc.citation.volume | 75 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 235 | - |
dc.citation.endPage | 240 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.subject.keywordPlus | C-REACTIVE PROTEIN | - |
dc.subject.keywordPlus | INSULIN-RESISTANCE | - |
dc.subject.keywordPlus | CARDIOVASCULAR-DISEASE | - |
dc.subject.keywordPlus | MECHANISMS | - |
dc.subject.keywordPlus | ATHEROSCLEROSIS | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | MICE | - |
dc.subject.keywordAuthor | C-reactive protein | - |
dc.subject.keywordAuthor | interleukin-6 | - |
dc.subject.keywordAuthor | interleukin-10 | - |
dc.subject.keywordAuthor | adiponectin | - |
dc.subject.keywordAuthor | metabolic syndrome | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
145 Anam-ro, Seongbuk-gu, Seoul, 02841, Korea+82-2-3290-2963
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.