A minimally invasive flexible electrode array for simultaneous recording of ECoG signals from multiple brain regions
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jeong, Ui-Jin | - |
dc.contributor.author | Lee, Jungpyo | - |
dc.contributor.author | Chou, Namsun | - |
dc.contributor.author | Kim, Kanghwan | - |
dc.contributor.author | Shin, Hyogeun | - |
dc.contributor.author | Chae, Uikyu | - |
dc.contributor.author | Yu, Hyun-Yong | - |
dc.contributor.author | Cho, Il-Joo | - |
dc.date.accessioned | 2021-11-18T04:40:48Z | - |
dc.date.available | 2021-11-18T04:40:48Z | - |
dc.date.created | 2021-08-30 | - |
dc.date.issued | 2021-06-21 | - |
dc.identifier.issn | 1473-0197 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/127835 | - |
dc.description.abstract | The minimal invasiveness of electrocorticography (ECoG) enabled its widespread use in clinical areas as well as in neuroscience research. However, most existing ECoG arrays require that the entire surface area of the brain that is to be recorded be exposed through a large craniotomy. We propose a device that overcomes this limitation, i.e., a minimally invasive, polyimide-based flexible array of electrodes that can enable the recording of ECoG signals in multiple regions of the brain with minimal exposure of the surface of the brain. Magnetic force-assisted positioning of a flexible electrode array enables recording from distant brain regions with a small cranial window. Also, a biodegradable organic compound used for attaching a magnet on the electrodes allows simple retrieval of the magnet. We demonstrate with an in vivo chronic recording that an implanted ECoG electrode array can record ECoG signals from the visual cortex and the motor cortex during a rat's free behavior. Our results indicate that the proposed device induced minimal damage to the animal. We expect the proposed device to be utilized for experiments for large-scale brain circuit analyses as well as clinical applications for intra-operative monitoring of epileptic activity. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.subject | OSCILLATIONS | - |
dc.subject | CORTEX | - |
dc.subject | CONNECTIVITY | - |
dc.subject | TRANSPARENT | - |
dc.subject | FREQUENCY | - |
dc.subject | RIPPLES | - |
dc.subject | SURFACE | - |
dc.subject | UTILITY | - |
dc.subject | RAT | - |
dc.title | A minimally invasive flexible electrode array for simultaneous recording of ECoG signals from multiple brain regions | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Yu, Hyun-Yong | - |
dc.identifier.doi | 10.1039/d1lc00117e | - |
dc.identifier.scopusid | 2-s2.0-85108019553 | - |
dc.identifier.wosid | 000647585400001 | - |
dc.identifier.bibliographicCitation | LAB ON A CHIP, v.21, no.12, pp.2383 - 2397 | - |
dc.relation.isPartOf | LAB ON A CHIP | - |
dc.citation.title | LAB ON A CHIP | - |
dc.citation.volume | 21 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 2383 | - |
dc.citation.endPage | 2397 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Biochemical Research Methods | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
dc.subject.keywordPlus | OSCILLATIONS | - |
dc.subject.keywordPlus | CORTEX | - |
dc.subject.keywordPlus | CONNECTIVITY | - |
dc.subject.keywordPlus | TRANSPARENT | - |
dc.subject.keywordPlus | FREQUENCY | - |
dc.subject.keywordPlus | RIPPLES | - |
dc.subject.keywordPlus | SURFACE | - |
dc.subject.keywordPlus | UTILITY | - |
dc.subject.keywordPlus | RAT | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.