Aromatic and Aliphatic Apiuronides from the Bark of Cinnamomum cassia
- Authors
- Chang, Suk Woo; Lee, Jin Su; Lee, Ji Hwan; Kim, Ji-Young; Hong, Jongki; Kim, Sun Kwang; Lee, Dongho; Jang, Dae Sik
- Issue Date
- 26-3월-2021
- Publisher
- AMER CHEMICAL SOC
- Citation
- JOURNAL OF NATURAL PRODUCTS, v.84, no.3, pp.553 - 561
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF NATURAL PRODUCTS
- Volume
- 84
- Number
- 3
- Start Page
- 553
- End Page
- 561
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/128383
- DOI
- 10.1021/acs.jnatprod.0c01062
- ISSN
- 0163-3864
- Abstract
- Cinnamomum cassia Presl (Cinnamon) has been widely cultivated in the tropical or subtropical areas, such as Yunnan, Fujian, Guandong, and Hainan in China, as well as India, Vietnam, Thailand, and Malaysia. Four new glycosides bearing apiuronic acid (1, 4, 6, and 7) and their sodium or potassium salts (2, 3, and 5), together with 31 known compounds, were isolated from a hot water extract of the bark of C. cassia via repeated chromatography. The structures of the new compounds (1-7) were determined by NMR, IR, MS, and ICP-AES data and by acid hydrolysis and sugar analysis. This is the first report of the presence of apiuronic acid glycosides. Some of the isolates were evaluated for their analgesic effects on a neuropathic pain animal model induced by paclitaxel. Cinnzeylanol (8), cinnacaside (9), kelampayoside A (10), and syringaresinol (11) showed analgesic effects against paclitaxel-induced cold allodynia.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - Graduate School > Department of Plant Biotechnology > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.