Understanding the Connection Between the Gut–Brain Axis and Stress/Anxiety Disorders
- Authors
- Lee, Y.; Kim, Y.-K.
- Issue Date
- 5월-2021
- Publisher
- Springer
- Keywords
- Anxiety disorder; Gut–brain axis; Microbiota–gut–brain axis; Probiotics; Stress
- Citation
- Current Psychiatry Reports, v.23, no.5
- Indexed
- SCIE
SSCI
SCOPUS
- Journal Title
- Current Psychiatry Reports
- Volume
- 23
- Number
- 5
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/128933
- DOI
- 10.1007/s11920-021-01235-x
- ISSN
- 1523-3812
- Abstract
- Purpose of Review: We review the association of the microbiota-gut-brain axis and anxiety disorder or stress. Recent Finding: The microbiota–gut–brain axis mechanism encompasses a bidirectional relationship between the brain and gastrointestinal organs. Dysregulation of the microbiota–gut–brain axis has been actively revealed in the context of various psychiatric diseases such as neurodevelopmental disorders, schizophrenia, anxiety disorders, and depression. Summary: We suggest that onset of anxiety disorders may be correlated with activation of a microbiota–gut–brain mechanism involving the immune system, neurotransmitters, and the hormonal system. By applying a microbiota–gut–brain axis mechanism, the possibility of using gastrointestinal system drugs such as probiotics and antibiotics as treatments for anxiety disorders is a possibility. Although modification of the microbiota–gut–brain axis mechanism has yet to be adopted clinically, it is expected that novel strategies employing this mechanism will be developed and deployed as new treatments not only for anxiety disorders, but also other psychiatric diseases. © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.