Coagulation-Inspired Direct Fibrinogen Assay Using Plasmonic Nanoparticles Functionalized with Red Blood Cell Membranes
DC Field | Value | Language |
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dc.contributor.author | Kim, I. | - |
dc.contributor.author | Lee, D. | - |
dc.contributor.author | Lee, S.W. | - |
dc.contributor.author | Lee, J.H. | - |
dc.contributor.author | Lee, G. | - |
dc.contributor.author | Yoon, D.S. | - |
dc.date.accessioned | 2021-12-02T19:41:40Z | - |
dc.date.available | 2021-12-02T19:41:40Z | - |
dc.date.created | 2021-08-31 | - |
dc.date.issued | 2021-04-27 | - |
dc.identifier.issn | 1936-0851 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/128950 | - |
dc.description.abstract | The fast measurement of fibrinogen is essential in evaluating life-threatening sepsis and cardiovascular diseases. Here, we aim to utilize biomimetic plasmonic Au nanoparticles using red blood cell membranes (RBCM-AuNPs) and demonstrate nanoscale coagulation-inspired fibrinogen detection via cross-linking between RBCM-AuNPs. The proposed biomimetic RBCM-AuNPs are highly suitable for fibrinogen detection because hemagglutination, occurring in the presence of fibrinogen, induces a shift in the localized surface plasmon resonance of the NPs. Specifically, when the two ends of the fibrinogen protein are bound to receptors on separate RBCM-AuNPs, cross-linking of the RBCM-AuNPs occurs, yielding a corresponding plasmon shift within 10 min. This coagulation-inspired fibrinogen detection method, with a low sample volume, high selectivity, and high speed, could facilitate the diagnosis of sepsis and cardiovascular diseases. © 2021 American Chemical Society. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | American Chemical Society | - |
dc.title | Coagulation-Inspired Direct Fibrinogen Assay Using Plasmonic Nanoparticles Functionalized with Red Blood Cell Membranes | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, G. | - |
dc.contributor.affiliatedAuthor | Yoon, D.S. | - |
dc.identifier.doi | 10.1021/acsnano.0c08136 | - |
dc.identifier.scopusid | 2-s2.0-85100660544 | - |
dc.identifier.wosid | 000645436800035 | - |
dc.identifier.bibliographicCitation | ACS Nano, v.15, no.4, pp.6386 - 6394 | - |
dc.relation.isPartOf | ACS Nano | - |
dc.citation.title | ACS Nano | - |
dc.citation.volume | 15 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 6386 | - |
dc.citation.endPage | 6394 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.subject.keywordPlus | ATOMIC-FORCE MICROSCOPY | - |
dc.subject.keywordPlus | CARDIOVASCULAR-DISEASES | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | INFLAMMATION | - |
dc.subject.keywordPlus | ADSORPTION | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordAuthor | cardiovascular disease | - |
dc.subject.keywordAuthor | coagulation-inspired | - |
dc.subject.keywordAuthor | integrin αIIbβ3 | - |
dc.subject.keywordAuthor | localized surface plasmon resonance | - |
dc.subject.keywordAuthor | red blood cell membrane | - |
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