Origami paper-based sample preconcentration using sequentially driven ion concentration polarization
DC Field | Value | Language |
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dc.contributor.author | Lee, J. | - |
dc.contributor.author | Yoo, Y.K. | - |
dc.contributor.author | Lee, D. | - |
dc.contributor.author | Kim, C. | - |
dc.contributor.author | Kim, K.H. | - |
dc.contributor.author | Lee, S. | - |
dc.contributor.author | Kwak, S. | - |
dc.contributor.author | Kang, J.Y. | - |
dc.contributor.author | Kim, H. | - |
dc.contributor.author | Yoon, D.S. | - |
dc.contributor.author | Hur, D. | - |
dc.contributor.author | Lee, J.H. | - |
dc.date.accessioned | 2021-12-03T09:41:34Z | - |
dc.date.available | 2021-12-03T09:41:34Z | - |
dc.date.created | 2021-08-31 | - |
dc.date.issued | 2021-03-07 | - |
dc.identifier.issn | 1473-0197 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/129090 | - |
dc.description.abstract | Ion concentration polarization (ICP) is one of the preconcentration techniques which can acquire a high preconcentration factor. Still, the main hurdles of ICP are its instability and low efficiency under physiological conditions with high ionic strength and abundant biomolecules. Here, we suggested a sequentially driven ICP process, which enhanced the electrokinetic force required for preconcentration, enabling enrichment of highly ionic raw samples without increasing the electric field. We acquired a 13-fold preconcentration factor (PF) in human serum using a paper-based origami structure consisting of multiple layers for three-dimensional sequential ICP (3D seq-ICP). Moreover, we demonstrated a paper-based enzyme-linked immunosorbent assay (ELISA) by 3D seq-ICP using tau protein, showing a 6-fold increase in ELISA signals. © The Royal Society of Chemistry 2021. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | Royal Society of Chemistry | - |
dc.title | Origami paper-based sample preconcentration using sequentially driven ion concentration polarization | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Yoon, D.S. | - |
dc.identifier.doi | 10.1039/d0lc01032d | - |
dc.identifier.scopusid | 2-s2.0-85102289214 | - |
dc.identifier.wosid | 000626710700002 | - |
dc.identifier.bibliographicCitation | Lab on a Chip, v.21, no.5, pp.867 - 874 | - |
dc.relation.isPartOf | Lab on a Chip | - |
dc.citation.title | Lab on a Chip | - |
dc.citation.volume | 21 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 867 | - |
dc.citation.endPage | 874 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Biochemical Research Methods | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
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