Early Recurrence Is Reliable Predictor of Late Recurrence After Radiofrequency Catheter Ablation of Atrial Fibrillation
- Authors
- Kim, Y.G.; Boo, K.Y.; Choi, J.-I.; Choi, Y.Y.; Choi, H.Y.; Roh, S.-Y.; Shim, J.; Kim, J.S.; Kim, Y.-H.
- Issue Date
- 3월-2021
- Publisher
- Elsevier Inc.
- Keywords
- atrial fibrillation; early recurrence; late recurrence; radiofrequency catheter ablation
- Citation
- JACC: Clinical Electrophysiology, v.7, no.3, pp.343 - 351
- Indexed
- SCIE
SCOPUS
- Journal Title
- JACC: Clinical Electrophysiology
- Volume
- 7
- Number
- 3
- Start Page
- 343
- End Page
- 351
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/129109
- DOI
- 10.1016/j.jacep.2020.09.029
- ISSN
- 2405-5018
- Abstract
- Objectives: This study aimed to compare the risk of late recurrence in patients with and without early recurrence. Background: Early recurrence of atrial fibrillation (AF) or atrial tachycardia (AT) after radiofrequency catheter ablation (RFCA) in AF patients is known to be a transient phenomenon. The theoretical basis of the blanking period is based on such observations. However, the clinical implications of early recurrence need further validation. Methods: Consecutive RFCA cases in a tertiary hospital were analyzed. Early recurrence was defined as any AT or AF event occurring within 90-days post-RFCA. Early recurrence as AT and AF were also analyzed separately. Results: A total of 3,120 patients underwent RFCA. Early recurrence occurred in 751 patients (24.1%). Patients who experienced early recurrence had a larger left atrium, worse hemodynamics in the left atrial appendage, and a higher prevalence of nonparoxysmal AF and heart failure. Among patients who experienced early recurrence, 69.6% of patients eventually had late recurrence. Early recurrence was associated with a 4.3- and 3.6-fold increase in the risk of late recurrence after single and multiple procedures, respectively. After multivariate adjustment, early recurrence was an independent risk factor for late recurrence with 3.6- and 2.8-fold increase in the risk of late recurrence after single and multiple procedures, respectively. Early recurrence AT had a lower risk of late recurrence compared with early recurrence AF. Conclusions: Early recurrence was a reliable predictor for late recurrence. The clinical significance of the blanking period in the current guidelines may need to be revisited. © 2021 American College of Cardiology Foundation
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Collections - Graduate School > Department of Biomedical Sciences > 1. Journal Articles
- College of Medicine > Department of Medical Science > 1. Journal Articles
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