Lipase-catalyzed synthesis of 2-ethylhexyl palmitate in a solvent free system using step changes in temperature
DC Field | Value | Language |
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dc.contributor.author | Choi, Suhyeon | - |
dc.contributor.author | Kim, Byung Hee | - |
dc.contributor.author | No, Da Som | - |
dc.contributor.author | Yoon, Sung Won | - |
dc.contributor.author | Lee, Moon-Won | - |
dc.contributor.author | Im, Dong Joong | - |
dc.contributor.author | Kim, In-Hwan | - |
dc.date.accessioned | 2022-02-11T02:41:56Z | - |
dc.date.available | 2022-02-11T02:41:56Z | - |
dc.date.created | 2022-02-09 | - |
dc.date.issued | 2022-01 | - |
dc.identifier.issn | 1369-703X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/135286 | - |
dc.description.abstract | Lipase-catalyzed synthesis of 2-ethylhexyl palmitate (2-EHP) from 2-ethylhocyl alcohol and palmitic acid was carried out in a solvent-free system. A commercial liquid lipase (Eversa Transform 2.0, Novozymes) from Thermomyces lanuginosus was immobilized on Lewatit VP OC 1600, a macroporous hydrophobic carrier. The efficacy of this Eversa immobilized lipase prepared in this study was evaluated on the synthesis of 2-EHP compared with that of Novozym 435 (from Candida antarctica), Lipozyme RM IM (from Rhizomucor miehei), Lipozyme TL IM (from Thermomyces lanuginosus), and the liquid Eversa lipase (commercial name: Eversa Transform 2.0). Among these lipases, the Eversa immobilized lipase was the most effective for the synthesis of 2-EHP. Optimum conditions for the synthesis of 2-EHP using this enzyme were a temperature of 55 degrees C and enzyme loading of 2% (based on the total weight of substrate). The conversion of 97% was achieved under these optimum conditions. Finally, as a cost-saving strategy, a step change in the reaction temperature was introduced. When a step change in the reaction temperature between 55 degrees C and 45 degrees C used, an identical degree of conversion was achieved compared to a constant reaction temperature of 55 degrees C throughout the reaction. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER | - |
dc.subject | ENZYMATIC-SYNTHESIS | - |
dc.subject | IMMOBILIZED LIPASE | - |
dc.subject | EMOLLIENTS | - |
dc.subject | ACID | - |
dc.subject | OIL | - |
dc.title | Lipase-catalyzed synthesis of 2-ethylhexyl palmitate in a solvent free system using step changes in temperature | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, In-Hwan | - |
dc.identifier.doi | 10.1016/j.bej.2021.108261 | - |
dc.identifier.scopusid | 2-s2.0-85118571264 | - |
dc.identifier.wosid | 000717092700020 | - |
dc.identifier.bibliographicCitation | BIOCHEMICAL ENGINEERING JOURNAL, v.177 | - |
dc.relation.isPartOf | BIOCHEMICAL ENGINEERING JOURNAL | - |
dc.citation.title | BIOCHEMICAL ENGINEERING JOURNAL | - |
dc.citation.volume | 177 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Engineering, Chemical | - |
dc.subject.keywordPlus | ENZYMATIC-SYNTHESIS | - |
dc.subject.keywordPlus | IMMOBILIZED LIPASE | - |
dc.subject.keywordPlus | EMOLLIENTS | - |
dc.subject.keywordPlus | ACID | - |
dc.subject.keywordPlus | OIL | - |
dc.subject.keywordAuthor | 2-Ethylhexyl palmitate | - |
dc.subject.keywordAuthor | Eversa immobilized lipase | - |
dc.subject.keywordAuthor | Hydrophobic carrier | - |
dc.subject.keywordAuthor | Step change | - |
dc.subject.keywordAuthor | Temperature | - |
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