Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Dynamics of inter-farm transmission of highly pathogenic avian influenza H5N6 integrating vehicle movements and phylogenetic information

Authors
Yoo, Dae-SungChun, Byung ChulKim, YounjungLee, Kwang-NyeongMoon, Oun-Kyoung
Issue Date
17-12월-2021
Publisher
NATURE PORTFOLIO
Citation
SCIENTIFIC REPORTS, v.11, no.1
Indexed
SCIE
SCOPUS
Journal Title
SCIENTIFIC REPORTS
Volume
11
Number
1
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/135401
DOI
10.1038/s41598-021-03284-x
ISSN
2045-2322
Abstract
Highly pathogenic avian influenza (HPAI) in poultry holdings commonly spreads through animal trade, and poultry production and health-associated vehicle (PPHaV) movement. To effectively control the spread of disease, it is essential that the contact structure via those movements among farms is thoroughly explored. However, few attempts have been made to scrutinize PPHaV movement compared to poultry trade. Therefore, our study aimed to elucidate the role of PPHaV movement on HPAI transmission. We performed network analysis using PPHaV movement data based on a global positioning system, with phylogenetic information of the isolates during the 2016-2017 HPAI H5N6 epidemic in the Republic of Korea. Moreover, the contribution of PPHaV movement to the spread of HPAI was estimated by Bayesian modeling. The network analysis revealed that there was the relationship between phylogenetic clusters and the contact network via PPHaV movement. Furthermore, the similarity of farm poultry species and the shared integrators between inter-linked infected premises (IPs) were associated with ties within the same phylogenetic clusters. Additionally, PPHaV movement among phylogenetically clustered IPs was estimated to contribute to approximately 30% of HPAI H5N6 infections in IPs on average. This study provides insight into how HPAI spread via PPHaV movement and scientific basis for control strategies.
Files in This Item
There are no files associated with this item.
Appears in
Collections
College of Medicine > Department of Medical Science > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Altmetrics

Total Views & Downloads

BROWSE