Evaluation of the combined effect of elevated temperature and cadmium toxicity on Daphnia magna using a simplified DEBtox model

Abstract

Thermal discharge and heatwaves under climate change may increase water temperature. In this study, the individual and combined effect of elevated temperature and cadmium (Cd) toxicity on somatic growth and reproduction of Daphnia magna was evaluated using a simplified dynamic energy budget model (DEBtox). The model predicted that the maximum body length (Lm) would be shorter (3.705 mm) at an elevated temperature of 25 degrees C than at 20 degrees C (3.974 mm), whereas the maximum reproduction rate ( Rm) would be higher at 25 degrees C (5.735) than at 20 degrees C (5.591). The somatic growth and reproduction of D. magna were significantly (p < 0.05) reduced with increasing Cd concentrations, and the reduction was greater at 25 than at 20 degrees C. Potentiation of Cd toxicity by elevated temperature was correctly simulated by assuming four toxicological modes of action influencing assimilation, somatic maintenance and growth, and reproduction. Overall, the population growth rate of D. magna was expected to decrease linearly with increasing Cd concentrations, and the decrease was expected to be higher at 25 than at 20 degrees C. These findings suggest a significant ecological risk of toxic metals at elevated temperature, with a mechanistic interpretation of the potentiation effect using a DEBtox modeling approach.