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Interrelationship between secondary metabolites and antioxidant capacities of Centella asiatica using bivariate and multivariate correlation analysesInterrelationship between secondary metabolites and antioxidant capacities of Centella asiatica using bivariate and multivariate correlation analyses

Other Titles
Interrelationship between secondary metabolites and antioxidant capacities of Centella asiatica using bivariate and multivariate correlation analyses
Authors
Shin, Hyun YoungKim, HoonJung, SoontagJeong, Eun-JinLee, Kyung-HaengBae, Yun-JungSuh, Hyung JooJang, Keum-IlYu, Kwang-Won
Issue Date
12월-2021
Publisher
SPRINGER SINGAPORE PTE LTD
Keywords
Antioxidant activity; Centella asiatica; Component-activity relationship; Drying method; Principal component analysis; Triterpenoid
Citation
APPLIED BIOLOGICAL CHEMISTRY, v.64, no.1, pp.1 - 10
Indexed
SCIE
SCOPUS
KCI
Journal Title
APPLIED BIOLOGICAL CHEMISTRY
Volume
64
Number
1
Start Page
1
End Page
10
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/135631
DOI
10.1186/s13765-021-00656-9
ISSN
2468-0834
Abstract
Centella asiatica L. Urban (CA) is a valuable medicinal herb that contains various bioactive secondary metabolites. In the present study, the harvested CA was divided into whole plant and leaf parts, and were heated-air-dried or freeze-dried. The dried CA was extracted under various extraction conditions to obtain 16 extracts, and their antioxidant activities were examined. Twelve types of secondary metabolites (five polyphenolic acids, four triterpenoids, and three flavonoids) were quantified in each extract. Finally, the intercorrelations between secondary metabolites and antioxidant activities were analyzed through statistical analyses, such as Pearson correlation coefficient, scatter plotting, and principal component analysis. The antioxidant capacities of CA might be primarily influenced by major triterpenoids such as madecassoside and asiaticoside, which showed high content in the ethanol extracts of freeze-dried leaf parts. The present study provides a valuable groundwork for the development of optimal extraction processes for C. asiatica L. as an antioxidant material.
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Suh, Hyung Joo
보건과학대학 (바이오시스템의과학부)
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