Demographic and Multimodal Imaging Features of Macular Telangiectasia Type 2: Korean Macular Telangiectasia Type 2 Study - Report No. 2
- Authors
- Kim, Young Ho; Chung, Yoo-Ri; Oh, Jaeryung; Kim, Seong-Woo; Lee, Christopher Seungkyu; Yun, Cheolmin; Lee, Boram; Ahn, So Min; Choi, Eun Young; Jang, Sungmin; Lee, Kihwang
- Issue Date
- 3-9월-2021
- Publisher
- TAYLOR & FRANCIS INC
- Keywords
- Macular telangiectasia type 2; multicentre study
- Citation
- OPHTHALMIC EPIDEMIOLOGY, v.28, no.5, pp.436 - 443
- Indexed
- SCIE
SCOPUS
- Journal Title
- OPHTHALMIC EPIDEMIOLOGY
- Volume
- 28
- Number
- 5
- Start Page
- 436
- End Page
- 443
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/136386
- DOI
- 10.1080/09286586.2021.1872088
- ISSN
- 0928-6586
- Abstract
- Purpose: To investigate the demographic and multimodal imaging features of macular telangiectasia (MacTel) type 2 in Korea and their relationship with visual acuity and the clinical stage. Methods: A retrospective multicentre cross-sectional study was conducted in six tertiary hospitals in Korea and the study included 84 patients. Demographic data and imaging data of fundus photography, fundus autofluorescence (FAF), confocal blue-light reflectance (CBR), fluorescein angiography (FAG), and optical coherence tomography (OCT) were collected. Results: The Korean patients with MacTel type 2 were predominantly female (75%), and the mean logMAR visual acuity was 0.282 +/- 0.280 at initial presentation. Most commonly presented signs were the loss of retinal transparency in fundus photographs (68.3%); increased autofluorescence in FAF (83.6%); increased blue reflectance involving the centre in CBR (68.0%); telangiectatic vessels in FAG (88.2%); and hyporeflective cavities in OCT (77.7%). The eyes diagnosed in the first half of the study period (2009-2014) showed a tendency to be diagnosed at more advanced severe stages than those diagnosed in the second half of the study period (2015-2019), using new severity scales based on FAG, FAF and OCT findings. Conclusion: The clinical features of MacTel type 2 in Korean patients assessed by newer imaging modalities suggest that Korean patients and the Caucasian-dominant population show similar presentations. This study showed that MacTel type 2 can be diagnosed in the earlier phase of the disease by using new imaging modalities and through better understanding of the disease.
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