Characteristics, management, and clinical outcomes of patients with hospital-acquired and ventilator-associated pneumonia: A multicenter Cohort study in Korea
DC Field | Value | Language |
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dc.contributor.author | Ko, R.-E. | - |
dc.contributor.author | Min, K.H. | - |
dc.contributor.author | Hong, S.-B. | - |
dc.contributor.author | Baek, A.-R. | - |
dc.contributor.author | Lee, H.-K. | - |
dc.contributor.author | Cho, W.H. | - |
dc.contributor.author | Kim, C. | - |
dc.contributor.author | Chang, Y. | - |
dc.contributor.author | Lee, S.-S. | - |
dc.contributor.author | Oh, J.Y. | - |
dc.contributor.author | Lee, H.B. | - |
dc.contributor.author | Bae, S. | - |
dc.contributor.author | Moon, J.Y. | - |
dc.contributor.author | Yoo, K.H. | - |
dc.contributor.author | Jeon, K. | - |
dc.contributor.author | the Korean HAP/VAP Study Group | - |
dc.date.accessioned | 2022-03-10T00:41:58Z | - |
dc.date.available | 2022-03-10T00:41:58Z | - |
dc.date.created | 2022-02-09 | - |
dc.date.issued | 2021 | - |
dc.identifier.issn | 1738-3536 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/138406 | - |
dc.description.abstract | Background: Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) are significant public health issues in the world, but the epidemiological data pertaining to HAP/VAP is limited in Korea. The objective of this study was to investigate the characteristics, management, and clinical outcomes of HAP/VAP in Korea. Methods: This study is a multicenter retrospective cohort study. In total, 206,372 adult patients, who were hospitalized at one of the 13 participating tertiary hospitals in Korea, were screened for eligibility during the six-month study period. Among them, we included patients who were diagnosed with HAP/VAP based on the Infectious Diseases Society of America (IDSA)/American Thoracic Society (ATS) definition for HAP/VAP. Results: Using the IDSA/ATS diagnostic criteria, 526 patients were identified as HAP/VAP patients. Among them, 27.9% were diagnosed at the intensive care unit (ICU). The cohort of patients had a median age of 71.0 (range from 62.0 to 79.0) years. Most of the patients had a high risk of aspiration (63.3%). The pathogen involved was identified in 211 patients (40.1%). Furthermore, multidrug resistant (MDR) pathogens were isolated in 138 patients; the most common MDR pathogen was Acinetobacter baumannii. During hospitalization, 107 patients with HAP (28.2%) had to be admitted to the ICU for additional care. The hospital mortality rate was 28.1% in the cohort of this study. Among the 378 patients who survived, 54.2% were discharged and sent back home, while 45.8% were transferred to other hospitals or facilities. Conclusion: This study found that the prevalence of HAP/VAP in adult hospitalized patients in Korea was 2.54/1,000 patients. In tertiary hospitals in Korea, patients with HAP/VAP were elderly and had a risk of aspiration, so they were often referred to step-down centers. Copyright © 2021 The Korean Academy of Tuberculosis and Respiratory Diseases. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | Korean National Tuberculosis Association | - |
dc.title | Characteristics, management, and clinical outcomes of patients with hospital-acquired and ventilator-associated pneumonia: A multicenter Cohort study in Korea | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Oh, J.Y. | - |
dc.identifier.doi | 10.4046/TRD.2021.0018 | - |
dc.identifier.scopusid | 2-s2.0-85116811988 | - |
dc.identifier.bibliographicCitation | Tuberculosis and Respiratory Diseases, v.84, no.4, pp.317 - 325 | - |
dc.relation.isPartOf | Tuberculosis and Respiratory Diseases | - |
dc.citation.title | Tuberculosis and Respiratory Diseases | - |
dc.citation.volume | 84 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 317 | - |
dc.citation.endPage | 325 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002758698 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordAuthor | Epidemiology | - |
dc.subject.keywordAuthor | Healthcare-Associated Pneumonia | - |
dc.subject.keywordAuthor | Korea | - |
dc.subject.keywordAuthor | Mortality | - |
dc.subject.keywordAuthor | Ventilator-Associated Pneumonia | - |
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