Sequential double C- H functionalization of 2,5norbornadiene in flow
- Authors
- 김희진
- Issue Date
- 10월-2018
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- REACTION CHEMISTRY ENGINEERING, v.3, no.5, pp.635 - 639
- Indexed
- SCIE
SCOPUS
- Journal Title
- REACTION CHEMISTRY ENGINEERING
- Volume
- 3
- Number
- 5
- Start Page
- 635
- End Page
- 639
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/139727
- DOI
- 10.1039/c8re00131f
- ISSN
- 20589883
- Abstract
- An anionic species of 2,5-norbornadiene was generated and brominated using a flow reactor. In the second step, 2-bromo-2,5-norbornadiene was lithiated with LTMP and reacted with tributyltin chloride. Finally, an integrated one-flow synthesis using various electrophiles was achieved within 3 min to prepare 2-bromo-2,5-norbornadienes bearing a functional group at the 3-position.
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Collections - College of Science > Department of Chemistry > 1. Journal Articles
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