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Flash synthesis of TAC-101 and its analogues from 1,3,5-tribromobenzene using integrated flow microreactor systems
- Authors
- 김희진
- Issue Date
- 10월-2011
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- RSC ADVANCES, v.1, no.5, pp.758 - 760
- Indexed
- SCIE
SCOPUS
- Journal Title
- RSC ADVANCES
- Volume
- 1
- Number
- 5
- Start Page
- 758
- End Page
- 760
- ISSN
- 20462069
- Abstract
- Sequential introduction of three electrophiles into 1,3,5-tribromobenzene based on Br/Li exchange reaction was achieved using an integrated flow microreactor system consisting of six micromixers and six microtube reactors. This method enables flash synthesis of TAC-101 and its analogues within 13 s in good yields on a preparative scale.
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Collections - College of Science > Department of Chemistry > 1. Journal Articles
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