A human pluripotent stem cell line KUMi004-A generated from a patient with chronic lymphocytic leukemia

Kim, Ji-Hea; Kang, Ka-Won; Lee, Byung-Hyun; Park, Young; Sung, Hwa Jung; Kim, Byung-Soo

doi:10.1016/j.scr.2022.102668

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A human pluripotent stem cell line KUMi004-A generated from a patient with chronic lymphocytic leukemiaopen access

Authors: Kim, Ji-Hea; Kang, Ka-Won; Lee, Byung-Hyun; Park, Young; Sung, Hwa Jung; Kim, Byung-Soo

Issue Date: Apr-2022

Publisher: ELSEVIER

Citation: STEM CELL RESEARCH, v.60

Indexed: SCIE
SCOPUS

Journal Title: STEM CELL RESEARCH

Volume: 60

URI: https://scholar.korea.ac.kr/handle/2021.sw.korea/141863

DOI: 10.1016/j.scr.2022.102668

ISSN: 1873-5061

Abstract: Chronic lymphocytic leukemia (CLL) is a type of blood cancer caused by the abnormal accumulation of malignant plasma cells. In this study, we generated CLL iPSCs (KUMi004-a) using the Sendai virus, confirming pluripotency. Also, it can differentiate into three primary germ layers. We expect this cell line could be helpful to understand the pathology of CLL.

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Appears in Collections: Graduate School > Department of Biomedical Sciences > 1. Journal Articles

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