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A human pluripotent stem cell line KUMi004-A generated from a patient with chronic lymphocytic leukemiaopen access

Authors
Kim, Ji-HeaKang, Ka-WonLee, Byung-HyunPark, YoungSung, Hwa JungKim, Byung-Soo
Issue Date
4월-2022
Publisher
ELSEVIER
Citation
STEM CELL RESEARCH, v.60
Indexed
SCIE
SCOPUS
Journal Title
STEM CELL RESEARCH
Volume
60
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/141863
DOI
10.1016/j.scr.2022.102668
ISSN
1873-5061
Abstract
Chronic lymphocytic leukemia (CLL) is a type of blood cancer caused by the abnormal accumulation of malignant plasma cells. In this study, we generated CLL iPSCs (KUMi004-a) using the Sendai virus, confirming pluripotency. Also, it can differentiate into three primary germ layers. We expect this cell line could be helpful to understand the pathology of CLL.
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