Laboratory information management system for COVID-19 non-clinical efficacy trial data
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 윤수현 | - |
dc.contributor.author | 노현아 | - |
dc.contributor.author | 진희진 | - |
dc.contributor.author | 이성영 | - |
dc.contributor.author | 한소율 | - |
dc.contributor.author | 김성희 | - |
dc.contributor.author | 김지선 | - |
dc.contributor.author | 서정선 | - |
dc.contributor.author | 김정진 | - |
dc.contributor.author | 박인호 | - |
dc.contributor.author | 오주연 | - |
dc.contributor.author | 배준용 | - |
dc.contributor.author | 이지은 | - |
dc.contributor.author | 우선제 | - |
dc.contributor.author | 서선민 | - |
dc.contributor.author | 김나원 | - |
dc.contributor.author | 이연우 | - |
dc.contributor.author | 장희정 | - |
dc.contributor.author | 홍승민 | - |
dc.contributor.author | 안세희 | - |
dc.contributor.author | 류광수 | - |
dc.contributor.author | 염민주 | - |
dc.contributor.author | 이한별 | - |
dc.contributor.author | 정버드 | - |
dc.contributor.author | 윤선우 | - |
dc.contributor.author | 강정아 | - |
dc.contributor.author | 석상혁 | - |
dc.contributor.author | 이유진 | - |
dc.contributor.author | 김서연 | - |
dc.contributor.author | 김영빈 | - |
dc.contributor.author | 황지연 | - |
dc.contributor.author | 온다인 | - |
dc.contributor.author | 임수연 | - |
dc.contributor.author | 김솔빈 | - |
dc.contributor.author | 장지윤 | - |
dc.contributor.author | 이호 | - |
dc.contributor.author | 김경미 | - |
dc.contributor.author | 이효정 | - |
dc.contributor.author | 김홍빈 | - |
dc.contributor.author | 박준원 | - |
dc.contributor.author | 정대균 | - |
dc.contributor.author | 송대섭 | - |
dc.contributor.author | 최강석 | - |
dc.contributor.author | 이호영 | - |
dc.contributor.author | 최양규 | - |
dc.contributor.author | 최정아 | - |
dc.contributor.author | 송만기 | - |
dc.contributor.author | 박만성 | - |
dc.contributor.author | 서준영 | - |
dc.contributor.author | 남기택 | - |
dc.contributor.author | 신전수 | - |
dc.contributor.author | 원성호 | - |
dc.contributor.author | 윤준원 | - |
dc.contributor.author | 성제경 | - |
dc.date.accessioned | 2022-09-24T17:40:29Z | - |
dc.date.available | 2022-09-24T17:40:29Z | - |
dc.date.created | 2022-09-23 | - |
dc.date.issued | 2022 | - |
dc.identifier.issn | 1738-6055 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/143909 | - |
dc.description.abstract | Background: As the number of large-scale studies involving multiple organizations producing data has steadily increased, an integrated system for a common interoperable format is needed. In response to the coronavirus disease 2019 (COVID-19) pandemic, a number of global efforts are underway to develop vaccines and therapeutics. We are therefore observing an explosion in the proliferation of COVID-19 data, and interoperability is highly requested in multiple institutions participating simultaneously in COVID-19 pandemic research. Results: In this study, a laboratory information management system (LIMS) approach has been adopted to systemically manage various COVID-19 non-clinical trial data, including mortality, clinical signs, body weight, body temperature, organ weights, viral titer (viral replication and viral RNA), and multiorgan histopathology, from multiple institutions based on a web interface. The main aim of the implemented system is to integrate, standardize, and organize data collected from laboratories in multiple institutes for COVID-19 non-clinical efficacy testings. Six animal biosafety level 3 institutions proved the feasibility of our system. Substantial benefits were shown by maximizing collaborative high-quality non-clinical research. Conclusions: This LIMS platform can be used for future outbreaks, leading to accelerated medical product development through the systematic management of extensive data from non-clinical animal studies. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | 한국실험동물학회 | - |
dc.title | Laboratory information management system for COVID-19 non-clinical efficacy trial data | - |
dc.title.alternative | Laboratory information management system for COVID-19 non-clinical efficacy trial data | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | 김경미 | - |
dc.identifier.doi | 10.1186/s42826-022-00127-2 | - |
dc.identifier.bibliographicCitation | Laboratory Animal Research, v.38, no.2, pp.119 - 127 | - |
dc.relation.isPartOf | Laboratory Animal Research | - |
dc.citation.title | Laboratory Animal Research | - |
dc.citation.volume | 38 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 119 | - |
dc.citation.endPage | 127 | - |
dc.type.rims | ART | - |
dc.identifier.kciid | ART002850875 | - |
dc.description.journalClass | 2 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordAuthor | SARS-CoV-2 | - |
dc.subject.keywordAuthor | COVID-19 | - |
dc.subject.keywordAuthor | Non-clinical | - |
dc.subject.keywordAuthor | Laboratory information management system | - |
dc.subject.keywordAuthor | Data | - |
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