Photo-immobilization of pseudozwitterionic polymers with balanced electrical charge for developing anti-coagulation surfaces

Abstract

This study aims to develop an economical coating agent that can easily impart excellent anti-coagulative property onto polymer surfaces. To this end, photo-reactable pseudozwitterionic polymer comprising cationic ammonium, anionic carboxylic acid, and photo-reactable phenyl azide group was synthesized via free-radical polymerization. Hydrophilicity, surface charge, surface elemental analysis, and antibiofouling properties of the coated substrates were evaluated after photo-immobilizing the pseudozwitterionic polymer on the PET substrate. The pseudozwitterionic polymer was successfully immobilized; the coated substrate showed excellent anti-biofouling properties. Photo-immobilization of the pseudozwitterionic polymer was also confirmed to be effective in imparting anti-biofouling property onto the fibrous filtration membrane. The immobilized pseudozwitterionic polymer effectively prevented membrane blockage and safely filtered platelets from blood plasma. (C) 2020 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.